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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood–brain barrier following hypoxia-reoxygenation stress

Fig. 1

Increased mRNA expression of Abcc1, Abcc2 and Abcc4 at the BBB following H/R. Female Sprague–Dawley rats were subjected to H/R (Hx = 6% O2, 1 h; R = 21% O2 for 10 min, 30 min or 1 h), normoxia (Nx), hypoxia (Hx), or administered the Nrf2 activator sulforaphane for 3 h. Results are expressed as mean ± SD of three experiments, with each group consisting of pooled microvessels from three individual animals. *p < 0.01

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