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Table 6 Results of routine CSF analysis for MS patients

From: The MRZ reaction in primary progressive multiple sclerosis

 

PPMS (n = 103)

RRMS (n = 100)

Comparison statistics

Total CSF cell count in/µl (range; SD)

4.1 (1–43; 5.9)

8.9 (1–47; 10.3)

p < 0.001

Intrathecal IgG synthesis in % (range; SD)

19.8 (0–75.4; 21.8)

21.6 (0–84.3; 25.0)

n.s.

Intrathecal IgA synthesis in % (range; SD)

3.8 (0–54.9; 12.6)

2.1 (0–47.4; 7.5)

n.s.

Intrathecal IgM synthesis in % (range; SD)

5.0 (0–92.4; 17.0)

6.1 (0–88.3; 16.8)

n.s.

IgG index (range; SD)

0.93 (0.45–2.83; 0.42)

1.02 (0.23–4.0; 0.65)

n.s.

QIgG × 10−3 (range; SD)

5.3 (2.0–16.9; 3.1)

5.2 (1.0–15.8; 3.3)

n.s.

IgG concentration in CSF in mg/l (range; SD)

60.7 (19.4–217.0; 42.4)

55.9 (9.1–206.0; 39.8)

n.s.

  1. PPMS primary progressive multiple sclerosis, RRMS relapsing-remitting multiple sclerosis, IgG immunoglobuline G, IgA immunoglobuline A, IgM immunoglobuline M, QIgG quotient of IgG, SD standard deviation, n.s not significant. All group values are expressed as means