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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Immunohistochemical and in situ hybridization study of urate transporters GLUT9/URATv1, ABCG2, and URAT1 in the murine brain

Fig. 5

Localization of mRNA of urate transporters in murine brain by fluorescence in situ hybridization. ac Merged bright field and fluorescence images are seen in the upper panels, while the lower panels show the fluorescence images alone. Green dots show Fast Blue signal observed with the Alexa 750 filter set, while the red dots show Fast Red signal observed with the Cy3 filter set. mRNA probes: Slc22a12 (URAT1), Slc2a9 (GLUT9), Abcg2 (ABCG2). Slc22a12 is expressed largely in the ependyma and less in the parenchyma, Slc2a9 is expressed in the ependyma and parenchyma and Abcg2 in the choroid plexus epithelium

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