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Table 1 Biological values of hCMEC/D3 and IMR90-derived BMECs under resting conditions

From: Cerebral hypoxia/ischemia selectively disrupts tight junctions complexes in stem cell-derived human brain microvascular endothelial cells

Cell type

hCMEC/D3

IMR90-derived BMECs

Cell density (× 103 cells/cm2)

128 ± 21

98 ± 19

TEER (Ω cm2)

40 ± 14

392 ± 113

Pe fluorescein (10−4 cm/min)

19 ± 8

2.44 ± 1.12

Metabolic activity (OD 490 nm)

1.26 ± 0.45

0.89 ± 0.34

  1. Average cell density, TEER, fluorescein permeability (Pe) and metabolic activity (MTS absorbance at 490 nm wavelength). Mean ± SD, n = 18 for TEER and Pe values
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Fluids and Barriers of the CNS

ISSN: 2045-8118