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Table 1 Markers of dementia and protein concentrations in lumbar (fraction 1) and cistern-near cerebrospinal fluid (fraction 8) (n = 16 pairs of samples)

From: Small cisterno-lumbar gradient of phosphorylated Tau protein in geriatric patients with suspected normal pressure hydrocephalus

  CSF protein (mg/l) Albumin (mg/l) Tau (pg/ml) PTau (pg/ml) Aβ1–42 (pg/ml) Aβ1–40 (pg/ml) Aβ1–42/Aβ1–40
Fraction 1 8 1 8 1 8 1 8 1 8 1 8 1 8
Median 433 353 253 202 188 210 26.5 27.0 985 955 12567 12576 0.077 0.075
25th percentile 309 240 177 138 145 151 22.5 24.2 765 783 11215 11045 0.065 0.065
75th percentile 513 427 288 234 280 265 35.0 36.3 1279 1191 15691 15465 0.088 0.087
Correlation between fraction 1 and 8 (r S ) 0.95* 0.91* 0.94* 0.98* 0.97* 0.93* 0.81*
Fraction 1 versus 8, p value; Wilcoxon signed rank test <0.0001 <0.0001 NS 0.02 NS NS NS
  1. NS difference not significant
  2. * p < 0.0001