Table 3 Biomarker levels in iNPH and controls (median and IQ range)
From: Amyloid mis-metabolism in idiopathic normal pressure hydrocephalus
iNPH | Controls | |
|---|---|---|
n = 20 | n = 20 | |
NFL (ng/L) | 1185 (731–2103) | 938 (610–2141) |
APL1β25 (ng/L) | 2591 (2296–2951) ↑ | 2180 (1898–2386)*** |
APL1β27 (ng/L) | 1083 (887–1177) ↑ | 874 (796–964)*** |
APL1β28 (ng/L) | 1423 (1317–1550) ↓ | 1621 (1422–1797)** |
Aβ38 (ng/L) | 502 (266–625) ↓ | 1114 (819–1445)*** |
Aβ40 (ng/L) | 3676 (2190–4748) ↓ | 7682 (6366–9809)*** |
Aβ42 (ng/L) | 241 (144–405) ↓ | 754 (493–1058)*** |
sAPPα (ng/mL) | 207 (157–259) ↓ | 416 (323–665)*** |
sAPPβ (ng/mL) | 119 (92–170) ↓ | 280 (182–389)*** |
YKL40 (ng/mL) | 122 (90–167) | 137 (104–177) |