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Table 3 Epidemiological data and CSF analysis in the control group

From: Increased CSF aquaporin-4, and interleukin-6 levels in dogs with idiopathic communicating internal hydrocephalus and a decrease after ventriculo-peritoneal shunting

Breed, age, gender, body weight

Routine CSF examination

CSF volume (mL)

AQP4 concentrations and total quantity

IL-6 concentrations and total quantity

Pug, 4 years male neutered, 4.6 kg

Protein 262 mg/L

RBC 0/μL

Cells 3/μL

2.4

AQP4: 11.25

Total AQP4 quantity 27

IL-6: 25 IU

Total IL-6 quantity 60

Dachshund, 9 years, male, 6 kg

Protein 256 mg/L

RBC 0/μL

Cells 1/μL

3.2

AQP4: 9.67

Total AQP4 quantity 30.94

IL-6: 24 IU

Total IL-6 quantity 76.8

Austrian hound, 3 years male, 26 kg

Protein 220 mg/L

RBC 0/μL

Cells 3/μL

3.14

AQP4: 9.0

Total AQP4 quantity 28.26

IL-6: 27 IU

Total IL-6 quantity 85.87

German Shepherd dog, male, 5 years, 22 kg

Protein 302 mg/L

RBC 0/μL

Cells 2/μL

4.2

AQP4: 12.33

Total AQP4 quantity 51.78

IL-6: 19 IU

Total IL-6 quantity 79.8

Beagle, male-neutered 2 years, 12 kg

Protein 286 mg/L

RBC 0/μL

Cells 1/μL

2.45

AQP4: 8.87

Total AQP4 quantity 21.74

IL-6: 42 IU

Total IL-6 quantity 102.9

Doberman, male, 4 years, 36 kg

Protein 120 mg/L

RBC 0/μL

Cells 1/μL

3.04

AQP4: 6.57

Total AQP4 quantity 19.97

IL-6: 20 IU

Total IL-6 quantity 60.8

French Bulldog female-neutered, 1,5 years, 8 kg

Protein 79 mg/L

RBC 0/μL

Cells 2/μL

3.4

AQP4: 9.1

Total AQP4 quantity 30.60

IL-6: 27 IU

Total IL-6 quantity 91.8

Bernese mountain dog, female, 6 years, 34 kg

Protein 265 mg/L

RBC 0/μL

Cells 3/μL

4

AQP4: 11.97

Total AQP4 quantity 47.86

IL-6: 22 IU

Total IL-6 quantity 88

Cavalier King Charles spaniel, female, 8 years, 6 kg

Protein 289 mg/L

RBC 0/μL

Cells 5/μL

3.2

AQP4: 11.52

Total AQP4 quantity 36.87

IL-6: 34 IU

Total IL-6 quantity 108.8

Doberman, female- neutered, 7 years, 29 kg

Protein 156 mg/L

RBC 0/μL

Cells 1/μL

3.21

AQP4: 8.03

Total AQP4 quantity 25.79

IL-6: 55 IU

Total IL-6 quantity 176.55

  1. CSF volume, aquaporin-4 (AQP4) and interleukin-6 (IL-6) concentrations in the control group. Both values have been multiplied with the total CSF volume, expressed as AQP4* and IL-6* to obtain the total quantity in CSF (CSF cerebrospinal fluid, RBC red blood cell count)