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Table 4 The marker of gliosis, GFAP, and AQP4 levels correlated with DTI parameter values in the periventricular white matter

From: Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus

ROI Immunostain DTI parameter R p
Corpus callosum GFAP FA −0.370 0.144
MD 0.306 0.232
AD 0.600 0.011*
RD 0.424 0.090*
OX-42 FA −0.086 0.743
MD 0.002 0.993
AD 0.352 0.165
RD 0.120 0.646
AQP4 FA −0.323 0.205
MD 0.191 0.462
AD 0.566 0.018*
RD 0.409 0.103
MBP FA 0.091 0.729
MD −0.031 0.903
AD 0.159 0.541
RD −0.115 0.660
Periventricular white matter GFAP FA −0.485 0.048*
MD 0.647 0.005*
AD 0.667 0.003*
RD 0.680 0.003*
OX-42 FA −0.495 0.043*
MD 0.292 0.256
AD 0.299 0.244
RD 0.213 0.411
AQP4 FA −0.640 0.006*
MD 0.799 <0.001*
AD 0.801 <0.001*
RD 0.829 <0.001*
MBP FA 0.346 0.174
MD −0.495 0.043*
AD −0.360 0.155
RD −0.458 0.064*
  1. FA fractional anisotropy, MD mean diffusivity, AD axial diffusivity, RD radial diffusivity, R the correlation coefficient
  2. * Statistically significant correlations = p < 0.05