Fig. 2

Box plots (mean ± standard error of mean) showing cross sectional ratio of the lateral ventricle frontal horn areas to the cerebrum on the magnetic resonance images. The 16-day images were obtained 2 days after kaolin injection, the 29-day images were 14 days after kaolin injection and immediately prior to onset of drug treatment, and the 45-day images were obtained at the end of the treatment period shortly prior to termination (n = 7 for NaCl and n = 6 for MgSO₄ each at all time points). In comparison to non-hydrocephalic controls (not shown) and previous time points the ventricles enlarged progressively at successive time points (p < 0.05). There were no significant differences between the MgSO₄ and NaCl treatment groups