Fig. 5

Essential-8 medium. a Drug uptake profile of rhodamine 123, BODIPY-prazosin and CM-DCFDA in presence of CsA, Ko143 or MK571. Drug uptakes of the same efflux substrates in absence of inhibitors were used as controls. Fluorescence in controls was arbitrarily set to 100 %. b Doxorubicin drug uptake profile in presence of CsA, Ko143 or MK571, * and ** denote P < 0.05 and P < 0.01 in comparison to C-Matrigel