Fig. 2

Matrigel origin impacts BMECs barrier properties. a, b TEER and sodium fluorescein permeabilities in IMR90-derived BMECs differentiated on B-, C- or T-Matrigel. Note the degraded barrier function of cells grown on C-Matrigel compared to the two other groups. * and ** denotes P < 0.05 and P < 0.01 in comparison to B-Matrigel. c Representative immunostained micrographs of P-gp, BCRP and MRP1 expression in purified BMECs monolayers. Scale bar = 40 µm