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Table 2 The sensitivity and specificity for the diagnostic accuracy of CSF-derived HGF binding affinity to c-Met receptor; a cut off value = 10.0 response units (RU) was used to diagnose septic meningitis in community-acquired and nosocomial meningitis

From: Hepatocyte growth factor in cerebrospinal fluid differentiates community-acquired or nosocomial septic meningitis from other causes of pleocytosis

Sub-groups Nosocomial fever
C-met affinity Meningitis Other infections Total
≥10 23 5 28
<10 10 71 81
Total 33 76 109
  1. Values represent the numbers of patients in each group. The sensitivity and specificity of the diagnostic test were 69.7 and 93.4 %, respectively (a: nosocomial meningitis/other febrile infections post neurosurgery) and 95.4 % respective 95.7 % (b: community acquired septic/aseptic meningitis)
Sub-groups Community acquired
C-met affinity Septic meningitis Aseptic meningitis Total
≥10 21 2 23
<10 1 45 46
Total 22 47 69
  1. Values represent the numbers of patients in each group. The sensitivity and specificity of the diagnostic test were 69.7 and 93.4 %, respectively (a: nosocomial meningitis/other febrile infections post neurosurgery) and 95.4 % respective 95.7 % (b: community acquired septic/aseptic meningitis)