Fig. 3
From: Adenosine receptor signaling: a key to opening the blood–brain door
Cells of the central nervous system (CNS) not only produce adenosine but are also regulated by adenosine. Cells of the CNS, such as astrocytes, microglia, pericytes and neuronal cells can produce adenosine or their activity/function is regulated by adenosine. Adenosine regulates the blood brain barrier permeability and is involved in neural transmission and glial cell immune function and metabolism