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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Endotoxin-induced inflammation down-regulates l-type amino acid transporter 1 (LAT1) expression at the blood–brain barrier of male rats and mice

Fig. 4

Semiquantitative image analysis results of LAT1 in situ hybridization and LAT1 immunofluorescence. A LAT1 hybridization signal was quantified in the rat cortex. Values represent area covered by vascular LAT1 hybridization signal. B, C LAT1 immunofluorescence was quantified in the rat and mouse hypothalamus, ventro-lateral to the hypothalamic paraventricular nucleus. Values represent the average brightness value of the immunofluorescence. Groups were compared by the non-parametric Kruskal–Wallis test and then by Dunn’s multiple comparison test. *P < 0.05; **P < 0.01; vs control; Samples sizes are n = 4 or 5 rats or mice/group

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Fluids and Barriers of the CNS

ISSN: 2045-8118