The chemokine CXCL13 is elevated in the cerebrospinal fluid of patients with neurosyphilis

Table 1 Clinical and CSF parameters

Subject #	Age (years)	Sex	Clinical syndrome	CSF WBC count (/μL) (Ref.: <5)	Protein CSF (mg/dL) (Ref.: <450)	Q_Alb × 10 (Ref.: <8)	VDRL (CSF) (titer) (Ref.: <1)	CXCL13 in CSF (pg/mL) (Ref.: <10)
Subject #	Age (years)	Sex	Clinical syndrome	CSF WBC count (/μL) (Ref.: <5)	Protein CSF (mg/dL) (Ref.: <450)	Q_Alb × 10 (Ref.: <8)	VDRL (CSF) (titer) (Ref.: <1)	Baseline	1 month	3 months
1	79	M	Encephalomyelitis	18	878	9.3	2	292.6	66.8	17.7
2	55	F	Multiple cranial nerve palsies	25	933	12.5	8	134	24	7.8
3	56	M	Encephalomyelitis, cranial nerve palsies	42	648	6.3	32	6,600	183	n.a.
4	51	M	Cerebral vasculitis	192	1,160	12.4	32	972	184	n.a.
5	39	M	Meningoencephalitis	13	2,150	17.5	4	7,140	138	10

Clinical, demographic, and CSF routine laboratory characteristics at baseline and CXCL13 levels in CSF at baseline and during follow-up in neurosyphilis patients. Venereal disease research laboratory (VDRL) titers >1 are regarded as positive.
WBC white blood cell, Q _Alb albumin CSF–serum quotient, n.a. not available, ref reference values.

ISSN: 2045-8118