Pre-exposure to nicotine for 14 days reduces ischemic-reperfusion-enhanced glucose transport rate. (A) [3H] D-Glucose transport (K
in; mL.sec−1.g−1) in normal and tMCAO animals. (B)
14[C]-Sucrose vascular volume (V
mL. g−1). Data represent mean ± SEM, n = 5–6 animals, *P < 0.05 **P < 0.01and ***P < 0.001 comparing the nicotine-infused group with the corresponding saline-infused sham group, #
P < 0.05 comparing the nicotine-infused tMCAO group and saline-infused sham group using one way ANOVA analysis of the variance and Bonferonni’s multiple comparison test.