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Table 2 CSF compartmentalization in the different fluid-filled spaces of the developing brain

From: Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation

  

% of cranial cavity

% of total CSF

Combined compartments

E19

P2

P9

E19

P2

P9

Hindbrain spaces

LR, Sasbl

2.42 ± 0.13

2.92 ± 0.32

1.83 ± 0.35

8.7 ± 0.5

14.6 ± 1.6

18.4 ± 3.5

Cerebellar subarachnoid spaces

SasCb, SasC

4.70 ± 0.51

2.51 ± 0.59

1.38 ± 0.29

16.8 ± 1.8

12.5 ± 2.9

13.9 ± 3.0

Ventricles

LV, 3Vv, 3Vd, Aq, 4V

3.12 ± 0.68

1.48 ± 0.26

0.52 ± 0.05

11.2 ± 2.4

7.4 ± 1.3

5.3 ± 0.5

Internal cisterns

Qci, AmbCi, VI

6.02 ± 0.61

4.93 ± 0.44

1.96 ± 0.20

21.5 ± 2.2

24.6 ± 2.2

19.7 ± 2.0

Cortical subarachnoid spaces

SasCx, Rhf, Sasd

6.38 ± 0.68

3.23 ± 0.58

1.55 ± 0.12

22.8 ± 2.4

16.1 ± 2.9

15.6 ± 1.2

Basal cisterns of the midbrain

OptCi, MBCi

1.45 ± 0.23

1.78 ± 0.28

0.81 ± 0.15

5.24 ± 0.8

8.9 ± 1.4

8.1 ± 1.5

Forebrain subarachnoid spaces

Cilt, Sasant, SasOb

3.86 ± 0.95

3.28 ± 0.65

1.90 ± 0.24

13.8 ± 3.4

16.4 ± 3.2

19.1 ± 2.5

  1. Data are mean +/− SD, n = 4 (E19, P9) or n = 5 (P2). See Table 1 for abbreviations.