No. | Diagnosis | Cells/μl | Albumin quotient (*103) | Intrathecal Ig fraction (%) | IgG(IF) (type)* | IgG(AIB) | IgGκ | IgGλ | fκ | fλ | IgGκ/IgGλ | fκ/fλ |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | MS | 5 | 2.5 | IgG 36%; IgM 30% | + (type 3) | n.d. | + | + | + | + | = | = |
2 | MS | 62 | 9.6 | IgG 65% | + (type 2) | n.d. | + | 0 | n.d. | n.d. | IgGκ only | n.d. |
3 | MS | 5 | 2.9 | IgG 30%, IgM 43% | + (type 2) | n.d. | + | + | + | + | = | fκ > fλ |
4 | MS | 5 | 4.5 | IgG 65% IgM 77% | + (type 3) | + | + | + | + | + | = | = |
5 | MS | 1 | 3.1 | 0 | + (type 3) | n.d. | + | + | n.d. | n.d. | = | n.d. |
6 | CIS | 6 | 3.4 | 0 | + (type 2) | n.d. | 0 | + | + | + | IgGλ only | fκ > fλ |
7 | CIS | 3 | 2.7 | 0 | + (type 3) | n.d. | + | + | + | + | = | fκ > fλ |
8 | CIS | 1 | 3.3 | 0 | + (type 2) | + | + | + | + | + | IgGλ > IgGκ | = |
9 | NB | 118 | 37.4 | IgM 70% | + (type 2) | + | + | + | + | + | IgGλ > IgGκ | = |
10 | NB | 469 | 30.0 | IgM 40% | + (type 2) | + | + | + | + | + | IgGκ > IgGλ | fκ > fλ |
11 | NB + MGUS | 145 | 30.0 | IgG 30% IgM 54% | +** (type 3 + type 5) | +** | +** | + | + | + | IgGλ > IgGκ | fκ > fλ |
12 | NB | 35 | 12.8 | 0 | 0 (type 1) | 0*** | 0*** | 0 | + | 0 | 1 IgGκ band only | fκ only |
13 | NB | 100 | 32.8 | IgM 42% | + (type 3) | + | + | + | n.d. | n.d. | = | n.d. |
14 | AIDS, cerebral toxoplasmosis | 7 | 10.5 | IgM 53% | 0 (type 4) | n.d. | + | + | + | + | = | fκ > fλ |
15 | AIDP | 3 | 11.2 | 0 | 0 (type 4) | 0 | 0 | 0 | + | 0 | negative | fκ only |
16 | AIDP -1st puncture | 1 | 51.5 | 0 | 0 (type 4) | 0 | 0 | 0 | + | + | negative | fκ > fλ |
17 | AIDP - 2nd puncture | 1 | 39.4 | 0 | 0(type 4) | 0 | 0 | 0 | + | 0 | negative | fκ only |
18 | Oculomotor nerve paresis | 3 | 6.7 | 0 | 0 (type 1) | n.d. | 0 | 0 | n.d. | n.d. | negative | n.d. |
19 | Neurodegenerative (parkinsonism) | 2 | 6.2 | 0 | 0 (type 1) | 0 | 0 | 0 | + | 0 | negative | 2 weak fκ bands |
20 | Tension headache | 5 | 6.4 | 0 | 0 (type 1) | 0 | 0 | 0 | 0 | 0 | negative | negative |
21 | Dorsalgias, myalgias | 0 | 5.3 | 0 | 0 (type 1) | 0 | 0 | 0 | 0 | 0 | negative | negative |
22 | Memory disturbance | 0 | 3.0 | 0 | 0 (type 1) | 0 | 0 | 0 | 0 | 0 | negative | negative |
23 | Acute central hemiparesis with complete regression (post-paroxysmal?; normal brain MRI) | 0 | 4.0 | 0 | 0 (type 4) | 0 | 0 | 0 | 0 | 0 | negative | negative |
24 | Posterior columns syndrome, unknown etiology | 3 | 21.0 | IgM 12% | 0 (type 1) | 0 | 0 | 0 | + | 0 | negative | fκ only |
25 | Lacunar stroke | 1 | 3.9 | 0 | 0 (type 1) | n.d. | 0 | 0 | n.d. | n.d. | negative | n.d. |
26 | Gait disturbance, unknown aetiology | 0 | 4.9 | 0 | 0 (type 1) | n.d. | 0 | 0 | n.d. | n.d. | negative | n.d. |
27 | Orthostatic hypotension (normal brain MRI) | 1 | 7.5 | 0 | 0 (type 1) | n.d. | 0 | 0 | 0 | 0 | negative | negative |
28 | Headache (brain CT negative) | 0 | 3.2 | 0 | 0 (type 4) | n.d. | 0 | 0 | 0 | 0 | negative | negative |
29 | Vertigo | 1 | 11.3 | 0 | 0 (type 4) | 0 | 0 | 0 | 0 | 0 | negative | negative |
30 | Peripheral facial palsy | 1 | 4.0 | 0 | 0 (type 1) | 0 | 0 | 0 | 0 | 0 | negative | negative |
31 | Lyme arthritis | 2 | 4.2 | 0 | 0 (type 4) | 0 | 0 | 0 | 0 | 0 | negative | negative |
32 | Polyneuropathy, lumbar disc prolapse | 1 | 7.4 | 0 | 0 (type 4) | 0 | 0 | 0 | 0 | 0 | negative | negative |
33 | Paraprotein (UK NEQAS sample 8/2011) | n.d. | n.d. | n.d. | 0**** (type 5) | 0**** | 0 | 0**** | 0 | 0 | negative | negative |