Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model

Table 1 Distribution of dextran following CED into rat striatum

Molecular weight	4 kDa		10 kDa		20 kDa		70 kDa		150 kDa
Time point	10 min	3 h	10 min	3 h	10 min	3 h	10 min	3 h	10 min	3 h
Interstitial spaces	+	-	+	-	+	-	+	+	+	+
Perivascular macrophages	+	+	+	+	+	+	+	+	+	+
Leptomeningeal macrophages	+	+	+	+	+	+	-	+	-	+

ISSN: 2045-8118