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Figure 6 | Fluids and Barriers of the CNS

Figure 6

From: Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model

Figure 6

CED using slow infusion rates and ramping regime. Slow infusion of 10 kDa dextran at 1 μl/min or use of a ramping regime did not prevent perivascular distribution. Stereological comparisons revealed no significant difference in uptake of 10 kDa Dextran by ED1-positive perivascular macrophages when infused at 1 or 2.5 μl/min or when a ramping regime was used. Each histogram bar represents mean cell counts from 3 striata +/- S.D.

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