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Table 1 CSF/serum quotients for albumin, IgG, IgA, IgM and MBL with individual CSF and serum concentrations of MBL in controls and patients with barrier dysfunctions

From: Mannan-binding lectin in cerebrospinal fluid: a leptomeningeal protein

  Normal Blood CSF Barrier function
Pat Q Alb × 103 Q IgG × 103 Q IgA × 103 Q IgM × 103 Q MBL × 103 MBL-CSF ng/ml MBL-S ng/ml
1 6,8 2.9 1.5 0.3 2,77 1,1 397
2 3,4 1.6 0.6 0.1 1,33 1,31 979
3 6,0 2.9 1.5 <0.3 5,21 1,96 376
4 3,7 1.8 0.9 <0.2 0,39 0,2 514
5 7,0 3.2 1.9 0.3 16,7 0,2 12
6 4,9 2.3 0.8 0.2 0,34 1,58 4598
7 5,0 2.2 1.3 0.2 1,58 1,15 728
8 6,2 2.7 1.3 <0.3 0,53 0,11 207
9 2,6 1.2 0.6 <0.1 0,27 0,27 985
10 5,6 3.0 1.7 0.3 1,39 0,82 589
11 3,4 1.5 0.6 0.1 6,00 1,82 303
12 4,1 2.2 1.1 <0.3 0,77 0,7 913
13 7,5 4.2 2.6 0.5 33,8 1,15 34
Blood CSF barrier dysfunction
14 13.4 7.2 4.0 0.5 12.75 0.88 69
15 10.3 5.2 3.1 1.1 0.61 1.14 6784
16 16.6 9.6 7.7 1.2 0.59 1.59 2678
17 36.7 32.2 22.8 13.6 5.00 6.79 1346
18 64.6 52.5 42.4 36.6 2.41 4.19 1739
19 24.8 11.3 7.6 0.9 0.64 2.16 3391
20 106 79.7 70.2 67.9 4.39 8.43 1921
  1. The control group (upper part) represents patients with normal CSF data and normal barrier function. The lower part represents the group of patients with a blood-CSF barrier dysfunction without signs of an inflammation in brain.