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Figure 5 | Fluids and Barriers of the CNS

Figure 5

From: Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus

Figure 5

Interaction between immunization treatment and time of analysis post-immunization on expression of immune-related genes within CP stromal capillary and choroidal epithelial compartments. Interactive effects of treatment (MOG-CFA/PTX, CFA-PTX and naïve) and time post-immunization were determined by two-way ANOVA on the 23 immune-related genes that were super-induced following MOG-CFA/PTX immunization in either of the two CP compartments (those genes graphed in Figures 3, 4A and B). Of these 23 genes, 13 genes in the CP stromal capillary and 4 genes in the CP epithelial tissue exhibited significant positive interaction between treatment and time post-immunization, and are denoted with their corresponding p values. The remaining genes that showed no significant interaction are labeled by (x). Time-dependent changes in expression of CCL19 in stromal capillary tissue and CXCL10 in choroidal epithelial tissue are graphed as representative examples * p < 0.05, ** p < 0.005.

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