Table 1 Patient data and antibody indices to six viral antigens in CSF samples negative for total-IgG oligoclonal bands
No. | Age | Sex | OCBs | AI Bb | AI HSV | AI VZV | AI CMV | AI MV | AI RV | CSF WCC | Suspected diagnosis and indicated by the sender |
|---|---|---|---|---|---|---|---|---|---|---|---|
#1A | 32 | M | NEG/NEG | Not det. | 0.72 | 0.74 | Not det. | 0.69 | 0.77 | 1557 | CSF PCR positive HSV encephalitis |
#1B | 32 | M | NEG/NEG | Not det. | 43.40 | 1.24 | Not det. | ND | ND | 1456 | CSF PCR positive HSV encephalitis, follow-up 19 days later |
#1C | 32 | M | NEG/NEG | ND | 53.40 | 16.30 # | ND | ND | ND | 152 | CSF PCR positive HSV encephalitis, follow-up a further 3 days later |
#2A | 33 | M | NEG/NEG | Not det. | 2.02 | 1.54 | ND | ND | 0.83 | No data | Blistering rash V2, peripheral facialis paresis |
#2B | 33 | M | NEG/NEG | ND | 1.94 | 1.39 | ND | ND | ND | 19 | Blistering rash V2, peripheral facialis paresis, follow-up 8 days later |
#3 | 30 | M | NEG/NEG | ND | 2.43 | 1.12 | ND | 0.85 | 1.10 | 2 | No data available |
#4 | 29 | F | NEG/NEG | Not det. | 2.12 | 0.99 | 1.30 | ND | 0.94 | 3 | No data available |
#5A | 34 | F | NEG/NEG | Not det. | ND | ND | ND | ND | ND | No data | VZV meningoencephalitis |
#5B | 34 | F | NEG/NEG | ND | Not det. | 3.99 | Not det. | ND | ND | 360 | VZV meningoencephalitis, follow-up 5 days later |
#6 | 60 | F | NEG/NEG | Not det. | 1.20 | 2.40 | 0.86 | ND | ND | 2 | “FK506-associated leukoencephalopathy”, grand mal |
#7 | 51 | M | NEG/NEG | 1.26 | 1.11 | 2.42 | 1.03 | 0.90 | 1.03 | 1 | “Fatigue and apathy” |
#8 | 42 | M | NEG/NEG | Not det. | 1.31 | 3.26 | ND | 1.03 | 1.32 | 3 | “Possible multiple sclerosis“ |
#9 | 74 | F | NEG/NEG | ND | 1.43 | 2.30 | Not det. | ND | 0.81 | 2 | No data available |
#10 | 50 | F | NEG/NEG | ND | Not det. | 2.00 | ND | 0.85 | 0.67 | No data | No data available |
#11 | 71 | F | POS/POS* | 20.90 | 1.45 | 1.32 | Not det. | 0.97 | 0.91 | 4 | Neuroborreliosis, encephalitis |
#12A | 34 | F | NEG/NEG | 2.60 | 0.91 | 0.80 | Not det. | 0.70 | 0.80 | 82 | Neuroborreliosis with abducens and facial nerve paresis |
#12B | 34 | F | NEG/NEG | 1.70 | 0.91 | 0.95 | Not det. | 1.15 | 0.83 | 277 | Confirmatory follow-up sample obtained 5 days later |
#13 | 44 | M | NEG/NEG | 10.60 | 0.90 | 1.00 | 0.88 | 1.5 | ND | No data | "Aseptic Meningitis” |
#14 | 84 | M | NEG/NEG | 5.31 | 1.02 | 0.99 | 0.85 | 1.02 | 1.04 | 2 | No data available |
#15 | 34 | F | NEG/NEG | 4.79 | Not det. | 0.99 | Not det. | 0.92 | ND | 1 | No data available |
#16 | 57 | M | NEG/NEG | 3.30 | 0.96 | 0.88 | 1.20 | 0.76 | 0.75 | 1 | No data available |
#17 | 21 | M | NEG/NEG | 2.50 | Not det. | 0.85 | Not det. | ND | 0.85 | 1 | No data available |
#18 | 38 | F | NEG/NEG | ND | 1.67 | 1.00 | 2.40 | 0.44 | 0.94 | No data | “Encephalitis” |
#19 | 40 | F | NEG/NEG | Not det. | Not det. | 16.20 | 1.43 | 0.72 | 0.90 | No data | No data available |
#20 | 25 | F | NEG/NEG | Not det. | 0.92 | 1.00 | Not det. | ND | 2.10 | 1 | “Clinically possible multiple sclerosis (Poser)” |
#21 | 60 | M | NEG/NEG | ND | 0.85 | 0.87 | Not det. | 2.80 | 0.92 | No data | No data available |