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Figure 6 | Fluids and Barriers of the CNS

Figure 6

From: Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

Figure 6

Histological sections stained with H&E to show general features of inflammation and corresponding unstained sections to visualize regions of fluorescence due to dextrans surrounding blood vessels. Sections were taken from representative wild-type and transgenic mice following HBSS or PTx administration and correspond to the final imaging session on day 5 post injection. Original magnification 100×. Additional lectin stained sections identify activated microglia and macrophages from corresponding transgenic mice at 400× magnification. Arrows indicate lectin-labeled cells within the brain parenchyma.

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