Figure 4

(A) The average percentage of enhancing pixels within each brain slice that had intensity enhancement 20 % or greater at day 3 post injection for transgenic and wild-type mice. (B) A representative set of calculated difference maps obtained from a transgenic mouse following 20 µg/kg PTx on day 3. Significant differences were found in the 6 most posterior slices for both transgenic (tg) low and high PTx compared to both wild-type (wt) and tg HBSS. * differs from wt, p < 0.05, ** p < 0.01, *** p < 0.001 and + differs from tg HBSS, p < 0.05, ++ p < 0.01, +++ p < 0.001.