Figure 12
From: The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility
The importance of intracranial compliance in hydrocephalus management. In this work, intraventricular infusion tests were used to measure the slope of the pressure-volume curve. From this, the authors derive an intracranial elastance index - not the absolute elastance because they use diastolic pressures rather than mean pressure in the calculations - which is shown here to provide excellent separation between patients who improved (white) and those who did not improve (blue) following shunting. The elastance index used here is proportional to the inverse of intracranial compliance (figure reproduced with permission from Anile et al [129]).