From: Attenuation of prostaglandin E2 elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole
Protein expression level (fmol/μg protein)
Transporter
Saline
3 mg/kg LPS
Ratio
(LPS/Saline)
Mrp4
1.80 ± 0.20
1.50 ± 0.13
0.833
Oat3
1.25 ± 0.08
0.929 ± 0.068*
0.743
Oatp1a4
2.46 ± 0.31
1.50 ± 0.14**
0.610
Pgt
N.D.
-