Figure 7From: Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvesselsDEP-mediated Cyp1b1 upregulation involves AhR. Western blots showing Cyp1b1 protein expression; β-actin was used as loading control. DEP-mediated upregulation of Cyp1b1 protein expression in isolated rat brain microvessels is blocked with (A) actinomycin D, an inhibitor of transcription, (B) cycloheximide (CHX), an inhibitor of protein synthesis, and (C) an AhR antagonist (CH-223191).Back to article page