Figure 5From: Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvesselsCyp1b1 protein expression in brain microvessels of TCDD-treated rats. Rats were administered a single dose of TCDD (25 μg/kg i.p.), and brain microvessels were isolated 12 h (A) and 72 h (B) after dosing. Rat microsomes were used as positive control for Cyp1b1 expression. The amount of Cyp1b1 in each sample was measured by densitometric analysis and normalized to β-actin.Back to article page