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Figure 2 | Fluids and Barriers of the CNS

Figure 2

From: Magnetic resonance imaging indicators of blood-brain barrier and brain water changes in young rats with kaolin-induced hydrocephalus

Figure 2

Subtractive contrast magnetic resonance imaging method. Coronal MR images (slices 1, 3, and 5) through a rat brain 1 week after kaolin injection demonstrating the subtractive method for quantitative detection of Gd-DTPA accumulation. The upper row shows T1-weighted images obtained prior to Gd-DTPA injection, the middle row shows T1-weighted images obtained 20 min after Gd-DTPA injection. Increased signal is apparent only in the periosteum (arrow) and vascular structures such as the superior sagittal sinus (arrowhead). The bottom row shows the calculated difference images. Note that the entire brain has increased signal due to detection of Gd-DTPA within the vasculature. Areas of extravasation (not evident in this example) would appear brighter. The white lines outline the brain region of interest selected for intensity measurements.

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Fluids and Barriers of the CNS

ISSN: 2045-8118