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Figure 3 | Fluids and Barriers of the CNS

Figure 3

From: 1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier

Figure 3

Effect of 1,25(OH) 2 D3 on the level of endogenous Aβ(1-40) in mouse brain. Mice received i.p. injection of 1,25(OH)2D3 (D3, 1 μg dissolved in 100 μL of H2O containing 5% ethanol) or vehicle (V, 100 μL of H2O containing 5% ethanol). After 24 h, brain levels of DEA-extracted mouse Aβ(1-40) were measured by ELISA. Each bar represents the mean ± SEM (n = 8). *p < 0.05, significantly different from vehicle-treated group.

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