TY - JOUR AU - Hiramatsu, M. PY - 2003 DA - 2003// TI - A role for guanidino compounds in the brain JO - Mol Cell Biochem VL - 244 UR - https://doi.org/10.1023/A:1022491419813 DO - 10.1023/A:1022491419813 ID - Hiramatsu2003 ER - TY - JOUR AU - Marescau, B. AU - De Deyn, P. AU - Wiechert, P. AU - Van Gorp, L. AU - Lowenthal, A. PY - 1986 DA - 1986// TI - Comparative study of guanidino compounds in serum and brain of mouse, rat, rabbit, and man JO - J Neurochem VL - 46 UR - https://doi.org/10.1111/j.1471-4159.1986.tb13030.x DO - 10.1111/j.1471-4159.1986.tb13030.x ID - Marescau1986 ER - TY - JOUR AU - Marescau, B. AU - Deshmukh, D. R. AU - Kockx, M. AU - Possemiers, I. AU - Qureshi, I. A. AU - Wiechert, P. AU - De Deyn, P. P. PY - 1992 DA - 1992// TI - Guanidino compounds in serum, urine, liver, kidney, and brain of man and some ureotelic animals JO - Metabolism VL - 41 UR - https://doi.org/10.1016/0026-0495(92)90213-T DO - 10.1016/0026-0495(92)90213-T ID - Marescau1992 ER - TY - JOUR AU - Wyss, M. AU - Kaddurah-Daouk, R. PY - 2000 DA - 2000// TI - Creatine and creatinine metabolism JO - Physiol Rev VL - 80 ID - Wyss2000 ER - TY - JOUR AU - Hosoya, K. AU - Hori, S. AU - Ohtsuki, S. AU - Terasaki, T. PY - 2004 DA - 2004// TI - A new in vitro model for blood-cerebrospinal fluid barrier transport studies: an immortalized choroid plexus epithelial cell line derived from the tsA58 SV40 large T-antigen gene transgenic rat JO - Adv Drug Deliv Rev VL - 56 UR - https://doi.org/10.1016/j.addr.2004.07.013 DO - 10.1016/j.addr.2004.07.013 ID - Hosoya2004 ER - TY - JOUR AU - Ohtsuki, S. AU - Terasaki, T. PY - 2007 DA - 2007// TI - Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development JO - Pharm Res VL - 24 UR - https://doi.org/10.1007/s11095-007-9374-5 DO - 10.1007/s11095-007-9374-5 ID - Ohtsuki2007 ER - TY - JOUR AU - Stockler, S. AU - Schutz, P. W. AU - Salomons, G. S. PY - 2007 DA - 2007// TI - Cerebral creatine deficiency syndromes: clinical aspects, treatment and pathophysiology JO - Subcell Biochem VL - 46 UR - https://doi.org/10.1007/978-1-4020-6486-9_8 DO - 10.1007/978-1-4020-6486-9_8 ID - Stockler2007 ER - TY - JOUR AU - Almeida, L. S. AU - Verhoeven, N. M. AU - Roos, B. AU - Valongo, C. AU - Cardoso, M. L. AU - Vilarinho, L. AU - Salomons, G. S. AU - Jakobs, C. PY - 2004 DA - 2004// TI - Creatine and guanidinoacetate: diagnostic markers for inborn errors in creatine biosynthesis and transport JO - Mol Genet Metab VL - 82 UR - https://doi.org/10.1016/j.ymgme.2004.05.001 DO - 10.1016/j.ymgme.2004.05.001 ID - Almeida2004 ER - TY - JOUR AU - Bianchi, M. C. AU - Tosetti, M. AU - Fornai, F. AU - Alessandri, M. G. AU - Cipriani, P. AU - De Vito, G. AU - Canapicchi, R. PY - 2000 DA - 2000// TI - Reversible brain creatine deficiency in two sisters with normal blood creatine level JO - Ann Neurol VL - 47 UR - https://doi.org/3.0.CO;2-N DO - 3.0.CO;2-N ID - Bianchi2000 ER - TY - JOUR AU - Item, C. B. AU - Stockler-Ipsiroglu, S. AU - Stromberger, C. AU - Muhl, A. AU - Alessandri, M. G. AU - Bianchi, M. C. AU - Tosetti, M. AU - Fornai, F. AU - Cioni, G. PY - 2001 DA - 2001// TI - Arginine:glycine amidinotransferase deficiency: the third inborn error of creatine metabolism in humans JO - Am J Hum Genet VL - 69 UR - https://doi.org/10.1086/323765 DO - 10.1086/323765 ID - Item2001 ER - TY - JOUR AU - Stockler, S. AU - Holzbach, U. AU - Hanefeld, F. AU - Marquardt, I. AU - Helms, G. AU - Requart, M. AU - Hanicke, W. AU - Frahm, J. PY - 1994 DA - 1994// TI - Creatine deficiency in the brain: a new, treatable inborn error of metabolism JO - Pediatr Res VL - 36 UR - https://doi.org/10.1203/00006450-199409000-00023 DO - 10.1203/00006450-199409000-00023 ID - Stockler1994 ER - TY - JOUR AU - Salomons, G. S. AU - van Dooren, S. J. AU - Verhoeven, N. M. AU - Cecil, K. M. AU - Ball, W. S. AU - Degrauw, T. J. AU - Jakobs, C. PY - 2001 DA - 2001// TI - X-linked creatine-transporter gene (SLC6A8) defect: a new creatine-deficiency syndrome JO - Am J Hum Genet VL - 68 UR - https://doi.org/10.1086/320595 DO - 10.1086/320595 ID - Salomons2001 ER - TY - JOUR AU - Persky, A. M. AU - Brazeau, G. A. PY - 2001 DA - 2001// TI - Clinical pharmacology of the dietary supplement creatine monohydrate JO - Pharmacol Rev VL - 53 ID - Persky2001 ER - TY - JOUR AU - Dechent, P. AU - Pouwels, P. J. AU - Wilken, B. AU - Hanefeld, F. AU - Frahm, J. PY - 1999 DA - 1999// TI - Increase of total creatine in human brain after oral supplementation of creatine-monohydrate JO - Am J Physiol VL - 277 ID - Dechent1999 ER - TY - JOUR AU - Stockler, S. AU - Hanefeld, F. AU - Frahm, J. PY - 1996 DA - 1996// TI - Creatine replacement therapy in guanidinoacetate methyltransferase deficiency, a novel inborn error of metabolism JO - Lancet VL - 348 UR - https://doi.org/10.1016/S0140-6736(96)04116-5 DO - 10.1016/S0140-6736(96)04116-5 ID - Stockler1996 ER - TY - JOUR AU - Bizzi, A. AU - Bugiani, M. AU - Salomons, G. S. AU - Hunneman, D. H. AU - Moroni, I. AU - Estienne, M. AU - Danesi, U. AU - Jakobs, C. AU - Uziel, G. PY - 2002 DA - 2002// TI - X-linked creatine deficiency syndrome: a novel mutation in creatine transporter gene SLC6A8 JO - Ann Neurol VL - 52 UR - https://doi.org/10.1002/ana.10246 DO - 10.1002/ana.10246 ID - Bizzi2002 ER - TY - JOUR AU - Cecil, K. M. AU - Salomons, G. S. AU - Ball, W. S. AU - Wong, B. AU - Chuck, G. AU - Verhoeven, N. M. AU - Jakobs, C. AU - DeGrauw, T. J. PY - 2001 DA - 2001// TI - Irreversible brain creatine deficiency with elevated serum and urine creatine: a creatine transporter defect? JO - Ann Neurol VL - 49 UR - https://doi.org/10.1002/ana.79 DO - 10.1002/ana.79 ID - Cecil2001 ER - TY - JOUR AU - Poo-Arguelles, P. AU - Arias, A. AU - Vilaseca, M. A. AU - Ribes, A. AU - Artuch, R. AU - Sans-Fito, A. AU - Moreno, A. AU - Jakobs, C. AU - Salomons, G. PY - 2006 DA - 2006// TI - X-Linked creatine transporter deficiency in two patients with severe mental retardation and autism JO - J Inherit Metab Dis VL - 29 UR - https://doi.org/10.1007/s10545-006-0212-4 DO - 10.1007/s10545-006-0212-4 ID - Poo-Arguelles2006 ER - TY - JOUR AU - Hiramatsu, M. AU - Edamatsu, R. AU - Fujikawa, N. AU - Shirasu, A. AU - Yamamoto, M. AU - Suzuki, S. AU - Mori, A. PY - 1988 DA - 1988// TI - Measurement during convulsions of guanidino compound levels in cerebrospinal fluid collected with a catheter inserted into the cisterna magna of rabbits JO - Brain Res VL - 455 UR - https://doi.org/10.1016/0006-8993(88)90111-4 DO - 10.1016/0006-8993(88)90111-4 ID - Hiramatsu1988 ER - TY - JOUR AU - Hosoya, K. AU - Yamamoto, A. AU - Akanuma, S. AU - Tachikawa, M. PY - 2010 DA - 2010// TI - Lipophilicity and transporter influence on blood-retinal barrier permeability: a comparison with blood-brain barrier permeability JO - Pharm Res VL - 27 UR - https://doi.org/10.1007/s11095-010-0272-x DO - 10.1007/s11095-010-0272-x ID - Hosoya2010 ER - TY - JOUR AU - Ohtsuki, S. AU - Tachikawa, M. AU - Takanaga, H. AU - Shimizu, H. AU - Watanabe, M. AU - Hosoya, K. AU - Terasaki, T. PY - 2002 DA - 2002// TI - The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain JO - J Cereb Blood Flow Metab VL - 22 UR - https://doi.org/10.1097/00004647-200211000-00006 DO - 10.1097/00004647-200211000-00006 ID - Ohtsuki2002 ER - TY - JOUR AU - Tachikawa, M. AU - Hosoya, K. AU - Ohtsuki, S. AU - Terasaki, T. PY - 2007 DA - 2007// TI - A novel relationship between creatine transport at the blood-brain and blood-retinal barriers, creatine biosynthesis, and its use for brain and retinal energy homeostasis JO - Subcell Biochem VL - 46 UR - https://doi.org/10.1007/978-1-4020-6486-9_5 DO - 10.1007/978-1-4020-6486-9_5 ID - Tachikawa2007 ER - TY - JOUR AU - Kakee, A. AU - Terasaki, T. AU - Sugiyama, Y. PY - 1996 DA - 1996// TI - Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier JO - J Pharmacol Exp Ther VL - 277 ID - Kakee1996 ER - TY - JOUR AU - Kitazawa, T. AU - Hosoya, K. AU - Takahashi, T. AU - Sugiyama, Y. AU - Terasaki, T. PY - 2000 DA - 2000// TI - In-vivo and in-vitro evidence of a carrier-mediated efflux transport system for oestrone-3-sulphate across the blood-cerebrospinal fluid barrier JO - J Pharm Pharmacol VL - 52 UR - https://doi.org/10.1211/0022357001773968 DO - 10.1211/0022357001773968 ID - Kitazawa2000 ER - TY - JOUR AU - Hosoya, K. AU - Tetsuka, K. AU - Nagase, K. AU - Tomi, M. AU - Saeki, S. AU - Ohtsuki, S. AU - Takanaga, H. AU - Yanai, N. AU - Obinata, M. AU - Kikuchi, A. PY - 2000 DA - 2000// TI - Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene JO - AAPS PharmSci VL - 2 UR - https://doi.org/10.1208/ps020328 DO - 10.1208/ps020328 ID - Hosoya2000 ER - TY - JOUR AU - Hosoya, K. AU - Takashima, T. AU - Tetsuka, K. AU - Nagura, T. AU - Ohtsuki, S. AU - Takanaga, H. AU - Ueda, M. AU - Yanai, N. AU - Obinata, M. AU - Terasaki, T. PY - 2000 DA - 2000// TI - mRna expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting JO - J Drug Target VL - 8 UR - https://doi.org/10.3109/10611860008997912 DO - 10.3109/10611860008997912 ID - Hosoya2000 ER - TY - JOUR AU - Kitazawa, T. AU - Hosoya, K. AU - Watanabe, M. AU - Takashima, T. AU - Ohtsuki, S. AU - Takanaga, H. AU - Ueda, M. AU - Yanai, N. AU - Obinata, M. AU - Terasaki, T. PY - 2001 DA - 2001// TI - Characterization of the amino acid transport of new immortalized choroid plexus epithelial cell lines: a novel in vitro system for investigating transport functions at the blood-cerebrospinal fluid barrier JO - Pharm Res VL - 18 UR - https://doi.org/10.1023/A:1011014424212 DO - 10.1023/A:1011014424212 ID - Kitazawa2001 ER - TY - JOUR AU - Terasaki, T. AU - Ohtsuki, S. AU - Hori, S. AU - Takanaga, H. AU - Nakashima, E. AU - Hosoya, K. PY - 2003 DA - 2003// TI - New approaches to in vitro models of blood-brain barrier drug transport JO - Drug Discov Today VL - 8 UR - https://doi.org/10.1016/S1359-6446(03)02858-7 DO - 10.1016/S1359-6446(03)02858-7 ID - Terasaki2003 ER - TY - JOUR AU - O'Kane, R. L. AU - Vina, J. R. AU - Simpson, I. AU - Zaragoza, R. AU - Mokashi, A. AU - Hawkins, R. A. PY - 2006 DA - 2006// TI - Cationic amino acid transport across the blood-brain barrier is mediated exclusively by system y+ JO - Am J Physiol Endocrinol Metab VL - 291 UR - https://doi.org/10.1152/ajpendo.00007.2006 DO - 10.1152/ajpendo.00007.2006 ID - O'Kane2006 ER - TY - JOUR AU - Stoll, J. AU - Wadhwani, K. C. AU - Smith, Q. R. PY - 1993 DA - 1993// TI - Identification of the cationic amino acid transporter (System y+) of the rat blood-brain barrier JO - J Neurochem VL - 60 UR - https://doi.org/10.1111/j.1471-4159.1993.tb13428.x DO - 10.1111/j.1471-4159.1993.tb13428.x ID - Stoll1993 ER - TY - JOUR AU - Aoyagi, K. PY - 2003 DA - 2003// TI - Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation JO - Mol Cell Biochem VL - 244 UR - https://doi.org/10.1023/A:1022479017087 DO - 10.1023/A:1022479017087 ID - Aoyagi2003 ER - TY - JOUR AU - Kamada, Y. AU - Nagaretani, H. AU - Tamura, S. AU - Ohama, T. AU - Maruyama, T. AU - Hiraoka, H. AU - Yamashita, S. AU - Yamada, A. AU - Kiso, S. AU - Inui, Y. PY - 2001 DA - 2001// TI - Vascular endothelial dysfunction resulting from L-arginine deficiency in a patient with lysinuric protein intolerance JO - J Clin Invest VL - 108 UR - https://doi.org/10.1172/JCI200111260 DO - 10.1172/JCI200111260 ID - Kamada2001 ER - TY - JOUR AU - Zlokovic, B. V. AU - Begley, D. J. AU - Chain, D. G. PY - 1983 DA - 1983// TI - Blood-brain barrier permeability to dipeptides and their constituent amino acids JO - Brain Res VL - 271 UR - https://doi.org/10.1016/0006-8993(83)91365-3 DO - 10.1016/0006-8993(83)91365-3 ID - Zlokovic1983 ER - TY - JOUR AU - Furuya, S. AU - Watanabe, M. PY - 2003 DA - 2003// TI - Novel neuroglial and glioglial relationships mediated by L-serine metabolism JO - Arch Histol Cytol VL - 66 UR - https://doi.org/10.1679/aohc.66.109 DO - 10.1679/aohc.66.109 ID - Furuya2003 ER - TY - JOUR AU - Yang, J. H. AU - Wada, A. AU - Yoshida, K. AU - Miyoshi, Y. AU - Sayano, T. AU - Esaki, K. AU - Kinoshita, M. O. AU - Tomonaga, S. AU - Azuma, N. AU - Watanabe, M. PY - 2010 DA - 2010// TI - Brain-specific Phgdh Deletion Reveals a Pivotal Role for L-Serine Biosynthesis in Controlling the Level of D-Serine, an N-methyl-D-aspartate Receptor Co-agonist, in Adult Brain JO - J Biol Chem VL - 285 UR - https://doi.org/10.1074/jbc.M110.187443 DO - 10.1074/jbc.M110.187443 ID - Yang2010 ER - TY - JOUR AU - Hosoya, K. AU - Sugawara, M. AU - Asaba, H. AU - Terasaki, T. PY - 1999 DA - 1999// TI - Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method JO - J Neurochem VL - 73 UR - https://doi.org/10.1046/j.1471-4159.1999.0731206.x DO - 10.1046/j.1471-4159.1999.0731206.x ID - Hosoya1999 ER - TY - JOUR AU - Kakee, A. AU - Takanaga, H. AU - Terasaki, T. AU - Naito, M. AU - Tsuruo, T. AU - Sugiyama, Y. PY - 2001 DA - 2001// TI - Efflux of a suppressive neurotransmitter, GABA, across the blood-brain barrier JO - J Neurochem VL - 79 UR - https://doi.org/10.1046/j.1471-4159.2001.00540.x DO - 10.1046/j.1471-4159.2001.00540.x ID - Kakee2001 ER - TY - JOUR AU - Lee, N. Y. AU - Kang, Y. S. PY - 2004 DA - 2004// TI - The brain-to-blood efflux transport of taurine and changes in the blood-brain barrier transport system by tumor necrosis factor-alpha JO - Brain Res VL - 1023 UR - https://doi.org/10.1016/j.brainres.2004.07.033 DO - 10.1016/j.brainres.2004.07.033 ID - Lee2004 ER - TY - JOUR AU - Takanaga, H. AU - Tokuda, N. AU - Ohtsuki, S. AU - Hosoya, K. AU - Terasaki, T. PY - 2002 DA - 2002// TI - ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline JO - Mol Pharmacol VL - 61 UR - https://doi.org/10.1124/mol.61.6.1289 DO - 10.1124/mol.61.6.1289 ID - Takanaga2002 ER - TY - JOUR AU - Kanai, Y. PY - 1997 DA - 1997// TI - Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications JO - Curr Opin Cell Biol VL - 9 UR - https://doi.org/10.1016/S0955-0674(97)80035-X DO - 10.1016/S0955-0674(97)80035-X ID - Kanai1997 ER - TY - JOUR AU - O'Kane, R. L. AU - Martinez-Lopez, I. AU - DeJoseph, M. R. AU - Vina, J. R. AU - Hawkins, R. A. PY - 1999 DA - 1999// TI - Na(+)-dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) of the blood-brain barrier. A mechanism for glutamate removal JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.45.31891 DO - 10.1074/jbc.274.45.31891 ID - O'Kane1999 ER - TY - JOUR AU - Benrabh, H. AU - Lefauconnier, J. M. PY - 1996 DA - 1996// TI - Glutamate is transported across the rat blood-brain barrier by a sodium-independent system JO - Neurosci Lett VL - 210 UR - https://doi.org/10.1016/0304-3940(96)12635-5 DO - 10.1016/0304-3940(96)12635-5 ID - Benrabh1996 ER - TY - JOUR AU - Lee, W. J. AU - Hawkins, R. A. AU - Vina, J. R. AU - Peterson, D. R. PY - 1998 DA - 1998// TI - Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal JO - Am J Physiol VL - 274 ID - Lee1998 ER - TY - JOUR AU - Tetsuka, K. AU - Takanaga, H. AU - Ohtsuki, S. AU - Hosoya, K. AU - Terasaki, T. PY - 2003 DA - 2003// TI - The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier JO - J Neurochem VL - 87 UR - https://doi.org/10.1046/j.1471-4159.2003.02063.x DO - 10.1046/j.1471-4159.2003.02063.x ID - Tetsuka2003 ER - TY - JOUR AU - Takanaga, H. AU - Ohtsuki, S. AU - Hosoya, K. AU - Terasaki, T. PY - 2001 DA - 2001// TI - GAT2/BGT-1 as a system responsible for the transport of gamma-aminobutyric acid at the mouse blood-brain barrier JO - J Cereb Blood Flow Metab VL - 21 UR - https://doi.org/10.1097/00004647-200110000-00012 DO - 10.1097/00004647-200110000-00012 ID - Takanaga2001 ER - TY - JOUR AU - Smith, K. E. AU - Borden, L. A. AU - Wang, C. H. AU - Hartig, P. R. AU - Branchek, T. A. AU - Weinshank, R. L. PY - 1992 DA - 1992// TI - Cloning and expression of a high affinity taurine transporter from rat brain JO - Mol Pharmacol VL - 42 ID - Smith1992 ER - TY - JOUR AU - Chen, N. H. AU - Reith, M. E. AU - Quick, M. W. PY - 2004 DA - 2004// TI - Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6 JO - Pflugers Arch VL - 447 UR - https://doi.org/10.1007/s00424-003-1064-5 DO - 10.1007/s00424-003-1064-5 ID - Chen2004 ER - TY - JOUR AU - Saltarelli, M. D. AU - Bauman, A. L. AU - Moore, K. R. AU - Bradley, C. C. AU - Blakely, R. D. PY - 1996 DA - 1996// TI - Expression of the rat brain creatine transporter in situ and in transfected HeLa cells JO - Dev Neurosci VL - 18 UR - https://doi.org/10.1159/000111450 DO - 10.1159/000111450 ID - Saltarelli1996 ER - TY - JOUR AU - Schloss, P. AU - Mayser, W. AU - Betz, H. PY - 1994 DA - 1994// TI - The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues JO - Biochem Biophys Res Commun VL - 198 UR - https://doi.org/10.1006/bbrc.1994.1093 DO - 10.1006/bbrc.1994.1093 ID - Schloss1994 ER - TY - JOUR AU - Tachikawa, M. AU - Fujinawa, J. AU - Takahashi, M. AU - Kasai, Y. AU - Fukaya, M. AU - Sakai, K. AU - Yamazaki, M. AU - Tomi, M. AU - Watanabe, M. AU - Sakimura, K. PY - 2008 DA - 2008// TI - Expression and possible role of creatine transporter in the brain and at the blood-cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant JO - J Neurochem VL - 107 UR - https://doi.org/10.1111/j.1471-4159.2008.05652.x DO - 10.1111/j.1471-4159.2008.05652.x ID - Tachikawa2008 ER - TY - JOUR AU - Tachikawa, M. AU - Kasai, Y. AU - Takahashi, M. AU - Fujinawa, J. AU - Kitaichi, K. AU - Terasaki, T. AU - Hosoya, K. PY - 2008 DA - 2008// TI - The blood-cerebrospinal fluid barrier is a major pathway of cerebral creatinine clearance: involvement of transporter-mediated process JO - J Neurochem VL - 107 UR - https://doi.org/10.1111/j.1471-4159.2008.05641.x DO - 10.1111/j.1471-4159.2008.05641.x ID - Tachikawa2008 ER - TY - JOUR AU - Shojaiefard, M. AU - Christie, D. L. AU - Lang, F. PY - 2005 DA - 2005// TI - Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3 JO - Biochem Biophys Res Commun VL - 334 UR - https://doi.org/10.1016/j.bbrc.2005.06.164 DO - 10.1016/j.bbrc.2005.06.164 ID - Shojaiefard2005 ER - TY - JOUR AU - Dodd, J. R. AU - Christie, D. L. PY - 2007 DA - 2007// TI - Selective amino acid substitutions convert the creatine transporter to a gamma-aminobutyric acid transporter JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M611705200 DO - 10.1074/jbc.M611705200 ID - Dodd2007 ER - TY - JOUR AU - Dominy, J. AU - Thinschmidt, J. S. AU - Peris, J. AU - Dawson, R. AU - Papke, R. L. PY - 2004 DA - 2004// TI - Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters JO - J Neurochem VL - 89 UR - https://doi.org/10.1111/j.1471-4159.2004.02410.x DO - 10.1111/j.1471-4159.2004.02410.x ID - Dominy2004 ER - TY - JOUR AU - Liu, Q. R. AU - Lopez-Corcuera, B. AU - Mandiyan, S. AU - Nelson, H. AU - Nelson, N. PY - 1993 DA - 1993// TI - Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected] JO - J Biol Chem VL - 268 ID - Liu1993 ER - TY - JOUR AU - Tachikawa, M. AU - Kasai, Y. AU - Yokoyama, R. AU - Fujinawa, J. AU - Ganapathy, V. AU - Terasaki, T. AU - Hosoya, K. PY - 2009 DA - 2009// TI - The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters JO - J Neurochem VL - 111 UR - https://doi.org/10.1111/j.1471-4159.2009.06332.x DO - 10.1111/j.1471-4159.2009.06332.x ID - Tachikawa2009 ER - TY - JOUR AU - Tomi, M. AU - Tajima, A. AU - Tachikawa, M. AU - Hosoya, K. PY - 2008 DA - 2008// TI - Function of taurine transporter (Slc6a6/TauT) as a GABA transporting protein and its relevance to GABA transport in rat retinal capillary endothelial cells JO - Biochim Biophys Acta VL - 1778 UR - https://doi.org/10.1016/j.bbamem.2008.04.012 DO - 10.1016/j.bbamem.2008.04.012 ID - Tomi2008 ER - TY - JOUR AU - Urakami, Y. AU - Kimura, N. AU - Okuda, M. AU - Inui, K. PY - 2004 DA - 2004// TI - Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney JO - Pharm Res VL - 21 UR - https://doi.org/10.1023/B:PHAM.0000029286.45788.ad DO - 10.1023/B:PHAM.0000029286.45788.ad ID - Urakami2004 ER - TY - JOUR AU - Kimura, N. AU - Masuda, S. AU - Katsura, T. AU - Inui, K. PY - 2009 DA - 2009// TI - Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2 JO - Biochem Pharmacol VL - 77 UR - https://doi.org/10.1016/j.bcp.2009.01.010 DO - 10.1016/j.bcp.2009.01.010 ID - Kimura2009 ER - TY - JOUR AU - Lightman, S. L. AU - Palestine, A. G. AU - Rapoport, S. I. AU - Rechthand, E. PY - 1987 DA - 1987// TI - Quantitative assessment of the permeability of the rat blood-retinal barrier to small water-soluble non-electrolytes JO - J Physiol VL - 389 UR - https://doi.org/10.1113/jphysiol.1987.sp016667 DO - 10.1113/jphysiol.1987.sp016667 ID - Lightman1987 ER - TY - JOUR AU - Sora, I. AU - Richman, J. AU - Santoro, G. AU - Wei, H. AU - Wang, Y. AU - Vanderah, T. AU - Horvath, R. AU - Nguyen, M. AU - Waite, S. AU - Roeske, W. R. PY - 1994 DA - 1994// TI - The cloning and expression of a human creatine transporter JO - Biochem Biophys Res Commun VL - 204 UR - https://doi.org/10.1006/bbrc.1994.2475 DO - 10.1006/bbrc.1994.2475 ID - Sora1994 ER - TY - JOUR AU - Guimbal, C. AU - Kilimann, M. W. PY - 1993 DA - 1993// TI - A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDNA cloning and functional expression JO - J Biol Chem VL - 268 ID - Guimbal1993 ER - TY - JOUR AU - Belanger, M. AU - Asashima, T. AU - Ohtsuki, S. AU - Yamaguchi, H. AU - Ito, S. AU - Terasaki, T. PY - 2007 DA - 2007// TI - Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro JO - Neurochem Int VL - 50 UR - https://doi.org/10.1016/j.neuint.2006.07.005 DO - 10.1016/j.neuint.2006.07.005 ID - Belanger2007 ER - TY - JOUR AU - Tachikawa, M. AU - Fukaya, M. AU - Terasaki, T. AU - Ohtsuki, S. AU - Watanabe, M. PY - 2004 DA - 2004// TI - Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis JO - Eur J Neurosci VL - 20 UR - https://doi.org/10.1111/j.1460-9568.2004.03478.x DO - 10.1111/j.1460-9568.2004.03478.x ID - Tachikawa2004 ER - TY - JOUR AU - Braissant, O. AU - Henry, H. AU - Loup, M. AU - Eilers, B. AU - Bachmann, C. PY - 2001 DA - 2001// TI - Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study JO - Brain Res Mol Brain Res VL - 86 UR - https://doi.org/10.1016/S0169-328X(00)00269-2 DO - 10.1016/S0169-328X(00)00269-2 ID - Braissant2001 ER - TY - JOUR AU - Balestrino, M. AU - Rebaudo, R. AU - Lunardi, G. PY - 1999 DA - 1999// TI - Exogenous creatine delays anoxic depolarization and protects from hypoxic damage: dose-effect relationship JO - Brain Res VL - 816 UR - https://doi.org/10.1016/S0006-8993(98)01131-7 DO - 10.1016/S0006-8993(98)01131-7 ID - Balestrino1999 ER - TY - JOUR AU - Brewer, G. J. AU - Wallimann, T. W. PY - 2000 DA - 2000// TI - Protective effect of the energy precursor creatine against toxicity of glutamate and beta-amyloid in rat hippocampal neurons JO - J Neurochem VL - 74 UR - https://doi.org/10.1046/j.1471-4159.2000.0741968.x DO - 10.1046/j.1471-4159.2000.0741968.x ID - Brewer2000 ER - TY - JOUR AU - Klivenyi, P. AU - Ferrante, R. J. AU - Matthews, R. T. AU - Bogdanov, M. B. AU - Klein, A. M. AU - Andreassen, O. A. AU - Mueller, G. AU - Wermer, M. AU - Kaddurah-Daouk, R. AU - Beal, M. F. PY - 1999 DA - 1999// TI - Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis JO - Nat Med VL - 5 UR - https://doi.org/10.1038/6568 DO - 10.1038/6568 ID - Klivenyi1999 ER - TY - JOUR AU - Matthews, R. T. AU - Ferrante, R. J. AU - Klivenyi, P. AU - Yang, L. AU - Klein, A. M. AU - Mueller, G. AU - Kaddurah-Daouk, R. AU - Beal, M. F. PY - 1999 DA - 1999// TI - Creatine and cyclocreatine attenuate MPTP neurotoxicity JO - Exp Neurol VL - 157 UR - https://doi.org/10.1006/exnr.1999.7049 DO - 10.1006/exnr.1999.7049 ID - Matthews1999 ER - TY - JOUR AU - Matthews, R. T. AU - Yang, L. AU - Jenkins, B. G. AU - Ferrante, R. J. AU - Rosen, B. R. AU - Kaddurah-Daouk, R. AU - Beal, M. F. PY - 1998 DA - 1998// TI - Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease JO - J Neurosci VL - 18 ID - Matthews1998 ER - TY - JOUR AU - Schmidt, A. AU - Marescau, B. AU - Boehm, E. A. AU - Renema, W. K. AU - Peco, R. AU - Das, A. AU - Steinfeld, R. AU - Chan, S. AU - Wallis, J. AU - Davidoff, M. PY - 2004 DA - 2004// TI - Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency JO - Hum Mol Genet VL - 13 UR - https://doi.org/10.1093/hmg/ddh112 DO - 10.1093/hmg/ddh112 ID - Schmidt2004 ER - TY - JOUR AU - Torremans, A. AU - Marescau, B. AU - Possemiers, I. AU - Van Dam, D. AU - D'Hooge, R. AU - Isbrandt, D. AU - De Deyn, P. P. PY - 2005 DA - 2005// TI - Biochemical and behavioural phenotyping of a mouse model for GAMT deficiency JO - J Neurol Sci VL - 231 UR - https://doi.org/10.1016/j.jns.2004.12.014 DO - 10.1016/j.jns.2004.12.014 ID - Torremans2005 ER - TY - JOUR AU - Neu, A. AU - Neuhoff, H. AU - Trube, G. AU - Fehr, S. AU - Ullrich, K. AU - Roeper, J. AU - Isbrandt, D. PY - 2002 DA - 2002// TI - Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism JO - Neurobiol Dis VL - 11 UR - https://doi.org/10.1006/nbdi.2002.0547 DO - 10.1006/nbdi.2002.0547 ID - Neu2002 ER - TY - JOUR AU - Keep, R. F. AU - Xiang, J. PY - 1996 DA - 1996// TI - Choroid plexus taurine transport JO - Brain Res VL - 715 UR - https://doi.org/10.1016/0006-8993(95)01294-X DO - 10.1016/0006-8993(95)01294-X ID - Keep1996 ER - TY - JOUR AU - Sijens, P. E. AU - Verbruggen, K. T. AU - Oudkerk, M. AU - van Spronsen, F. J. AU - Soorani-Lunsing, R. J. PY - 2005 DA - 2005// TI - 1H MR spectroscopy of the brain in Cr transporter defect JO - Mol Genet Metab VL - 86 UR - https://doi.org/10.1016/j.ymgme.2005.08.004 DO - 10.1016/j.ymgme.2005.08.004 ID - Sijens2005 ER - TY - JOUR AU - Braissant, O. AU - Henry, H. PY - 2008 DA - 2008// TI - AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: A review JO - J Inherit Metab Dis VL - 31 UR - https://doi.org/10.1007/s10545-008-0826-9 DO - 10.1007/s10545-008-0826-9 ID - Braissant2008 ER - TY - JOUR AU - Verbruggen, K. T. AU - Sijens, P. E. AU - Schulze, A. AU - Lunsing, R. J. AU - Jakobs, C. AU - Salomons, G. S. AU - van Spronsen, F. J. PY - 2007 DA - 2007// TI - Successful treatment of a guanidinoacetate methyltransferase deficient patient: findings with relevance to treatment strategy and pathophysiology JO - Mol Genet Metab VL - 91 UR - https://doi.org/10.1016/j.ymgme.2007.03.006 DO - 10.1016/j.ymgme.2007.03.006 ID - Verbruggen2007 ER - TY - JOUR AU - Mancardi, M. M. AU - Caruso, U. AU - Schiaffino, M. C. AU - Baglietto, M. G. AU - Rossi, A. AU - Battaglia, F. M. AU - Salomons, G. S. AU - Jakobs, C. AU - Zara, F. AU - Veneselli, E. AU - Gaggero, R. PY - 2007 DA - 2007// TI - Severe epilepsy in X-linked creatine transporter defect (CRTR-D) JO - Epilepsia VL - 48 UR - https://doi.org/10.1111/j.1528-1167.2007.01148.x DO - 10.1111/j.1528-1167.2007.01148.x ID - Mancardi2007 ER - TY - JOUR AU - Rosenberg, E. H. AU - Almeida, L. S. AU - Kleefstra, T. AU - deGrauw, R. S. AU - Yntema, H. G. AU - Bahi, N. AU - Moraine, C. AU - Ropers, H. H. AU - Fryns, J. P. AU - deGrauw, T. J. PY - 2004 DA - 2004// TI - High prevalence of SLC6A8 deficiency in X-linked mental retardation JO - Am J Hum Genet VL - 75 UR - https://doi.org/10.1086/422102 DO - 10.1086/422102 ID - Rosenberg2004 ER - TY - JOUR AU - Rosenberg, E. H. AU - Martinez Munoz, C. AU - Betsalel, O. T. AU - van Dooren, S. J. AU - Fernandez, M. AU - Jakobs, C. AU - deGrauw, T. J. AU - Kleefstra, T. AU - Schwartz, C. E. AU - Salomons, G. S. PY - 2007 DA - 2007// TI - Functional characterization of missense variants in the creatine transporter gene (SLC6A8): improved diagnostic application JO - Hum Mutat VL - 28 UR - https://doi.org/10.1002/humu.20532 DO - 10.1002/humu.20532 ID - Rosenberg2007 ER - TY - JOUR AU - Almeida, L. S. AU - Salomons, G. S. AU - Hogenboom, F. AU - Jakobs, C. AU - Schoffelmeer, A. N. PY - 2006 DA - 2006// TI - Exocytotic release of creatine in rat brain JO - Synapse VL - 60 UR - https://doi.org/10.1002/syn.20280 DO - 10.1002/syn.20280 ID - Almeida2006 ER - TY - JOUR AU - De Deyn, P. P. AU - Vanholder, R. AU - Eloot, S. AU - Glorieux, G. PY - 2009 DA - 2009// TI - Guanidino compounds as uremic (neuro)toxins JO - Semin Dial VL - 22 UR - https://doi.org/10.1111/j.1525-139X.2009.00577.x DO - 10.1111/j.1525-139X.2009.00577.x ID - De Deyn2009 ER - TY - JOUR AU - De Deyn, P. P. AU - Marescau, B. AU - Cuykens, J. J. AU - Van Gorp, L. AU - Lowenthal, A. AU - De Potter, W. P. PY - 1987 DA - 1987// TI - Guanidino compounds in serum and cerebrospinal fluid of non-dialyzed patients with renal insufficiency JO - Clin Chim Acta VL - 167 UR - https://doi.org/10.1016/0009-8981(87)90088-X DO - 10.1016/0009-8981(87)90088-X ID - De Deyn1987 ER - TY - JOUR AU - De Deyn, P. P. AU - Marescau, B. AU - D'Hooge, R. AU - Possemiers, I. AU - Nagler, J. AU - Mahler, C. PY - 1995 DA - 1995// TI - Guanidino compound levels in brain regions of non-dialyzed uremic patients JO - Neurochem Int VL - 27 UR - https://doi.org/10.1016/0197-0186(95)00041-6 DO - 10.1016/0197-0186(95)00041-6 ID - De Deyn1995 ER - TY - JOUR AU - De Deyn, P. P. AU - D'Hooge, R. AU - Van Bogaert, P. P. AU - Marescau, B. PY - 2001 DA - 2001// TI - Endogenous guanidino compounds as uremic neurotoxins JO - Kidney Int Suppl VL - 78 UR - https://doi.org/10.1046/j.1523-1755.2001.07849.x DO - 10.1046/j.1523-1755.2001.07849.x ID - De Deyn2001 ER - TY - JOUR AU - Ku, C. P. AU - Passow, H. PY - 1980 DA - 1980// TI - Creatine and creatinine transport in old and young human red blood cells JO - Biochim Biophys Acta VL - 600 UR - https://doi.org/10.1016/0005-2736(80)90426-5 DO - 10.1016/0005-2736(80)90426-5 ID - Ku1980 ER - TY - JOUR AU - Nakayama, H. AU - Kitaichi, K. AU - Ito, Y. AU - Hashimoto, K. AU - Takagi, K. AU - Yokoi, T. AU - Ozaki, N. AU - Yamamoto, T. AU - Hasegawa, T. PY - 2007 DA - 2007// TI - The role of organic cation transporter-3 in methamphetamine disposition and its behavioral response in rats JO - Brain Res VL - 1184 UR - https://doi.org/10.1016/j.brainres.2007.09.072 DO - 10.1016/j.brainres.2007.09.072 ID - Nakayama2007 ER -