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Figure 4 | Fluids and Barriers of the CNS

Figure 4

From: Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP

Figure 4

Oligomeric Aβ immunoreactivity is intraneuronal. Top row: hippocampal NeuN (A) and oligomeric Aβ (B) immunoreactivity in a six-month-old tgAPP21 rat at 10 weeks post-kaolin showing a strong overlap of immunopositive neuronal cell bodies (C), ×400. Bottom row: Frontoparietal cortical NeuN (D) and oligomeric Aβ (E) immunoreactivity in a six-month-old tgAPP21 rat at 10 weeks post-kaolin also reveals a widespread concomitance of immunopositive neuronal cell bodies (F), ×200.

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