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Figure 2 | Fluids and Barriers of the CNS

Figure 2

From: Kaolin-induced chronic hydrocephalus accelerates amyloid deposition and vascular disease in transgenic rats expressing high levels of human APP

Figure 2

Effects of cisternal kaolin injection. (A) At 10 weeks post-kaolin injection, there is marked histiocytic and granulomatous inflammation composed of many macrophages filled with kaolin in the SAS at the base of the brain (here around the hypothalamus and 3rd ventricle). (B) At six months post-kaolin injection, the inflammation has subsided leaving scarring and blockage in the SAS (below the 3rd ventricle) and a few small collections of histiocytes in the ventricle walls, here the 3rd ventricle (arrow). Masson trichrome stain, ×200.

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Fluids and Barriers of the CNS

ISSN: 2045-8118