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Figure 2 | Fluids and Barriers of the CNS

Figure 2

From: Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation

Figure 2

CCL2 gene expression in CNS microvascular endothelial cells, astrocytes and other parenchymal cells isolated by LCM. Endothelial cells (A, D), astrocytes (B, E), and other parenchymal cells (C, F) were separately acquired by LCM from spinal cord tissue of mice injected with CFA/PTX (A-C) or immunized with MOG-CFA/PTX (D-F). Analyses were performed at D9, D16 and D23 following either injection regime and relative CCL2 mRNA levels are plotted on a log scale. Comparisons were made to naïve mice. *P ≤ 0.05; **P ≤ 0.01; and ***P ≤ 0.001. Data has been presented as mean +/− SEM. For each experiment, LCM was performed on tissue from three individual mice from each naïve, control (CFA/PTX) and EAE (MOG-CFA/PTX) group.

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Fluids and Barriers of the CNS

ISSN: 2045-8118