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Table 1 Comparison of composition of CSF and blood plasma

From: Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence

Component

Ref.

CSF

Blood plasma

 

Concentration/mg (100 ml)-1

Protein

a

16 to 38

6300 to 8500

Sugar

a

45 to 80

80 to 120

Amino acids

a

1.5 to 3

4.5 to 9

Creatinine

a

0.5 to 2.2

0.7 to 2

Uric acid

a

0.4 to 2.8

2.9 to 6.9

Urea

a

5 to 39

22 to 42

Cholesterol

a

trace

100 to 150

Lactic acid

a

8 to 25

10 to 32

Phosphate (inorganic)

b

3.4

4.7

 

Concentration/mmol kg-1

Na+

b

147

150

K+

b

2.86

4.63

Ca2+

b

1.14

2.35

Mg2+

b

1.1

0.8

Cl−

b

113

99

b

23.3

26.8

pH

b

7.3

7.4

  1. Values are taken from the compilations in a) Millen and Woollam (1962) [2] based on data from Merritt and Fremont-Smith (1937) [31] and b) Davson and Segal (1996) [9].