Recruitment and exclusions in the reliability study. The participants were confirmed healthy regarding medical history and clinical examination including ongoing medication, physical and neurological examinations, electrocardiography, blood pressure, body mass index, Mini-Mental State Examination (MMSE) and MRI. Exclusion criteria was disease of the nervous system, MMSE < 28, medications affecting nervous system (such as benzodiazepine or antidepressants), anticoagulants, ischemic heart disease, diabetes, and vascular risk factors (Two of either: hypertension, smoking or hyperlipidemia). The attempt to obtain equal numbers of men and women, resulted in the early exclusion of 19 women who responded to the ad i.e. the “Remain” group.