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Figure 3 | Fluids and Barriers of the CNS

Figure 3

From: Increased blood–brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid

Figure 3

Brain microvessel area was not affected by intracisternal GA injection. (A) Confocal images of blood vessel profiles (white arrows) and microglia processes positive to lectin in both vehicle- and GA-injected animals at 14 and 30 DPI. (B) Quantitation of lectin-positive areas per field in manually-delineated small vessels (<10 μm in diameter) showing no significant differences in GA-injected animals with respect to controls. (C) Cresyl Violet staining of striatal sections evidencing the preservation of small blood vessel (black arrows) number and appearance. Note flattened endothelial cells lining the internal wall of capillaries in both vehicle- and GA-injected animals. Scale bars in A and C: 15 μm.

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