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Figure 4 | Fluids and Barriers of the CNS

Figure 4

From: Impedance-based cell monitoring: barrier properties and beyond

Figure 4

(A) Schematic impedance spectrum of a cell monolayer at different frequencies. (B) Equivalent electrical circuit diagram for a cell monolayer. At mid-range frequencies the cell-related parameters TEER and capacitance Ccl are contributing predominantly to the total impedance. At the lower end of the frequency range the spectrum is dominated by the capacity of the electrodes (CEl). At high frequencies the capacitors Ccl and Cel become increasingly conductive and the remaining total impedance converges to the resistance of the medium (RMedium). Adapted from [15] with permission.

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