Figure 3
From: Impedance-based cell monitoring: barrier properties and beyond
Equivalent circuit diagram describing the contribution of the trans- and paracellular pathway to the total impedance, Z, of the cellular system. TEER, transendothelial electric resistance; CEl, capacitance of the electrodes; CCl, capacitance of the cell layer; Rmedium, ohmic resistance of the medium; Rmembrane, ohmic resistance of the membranes. Please note that for most epithelial cells the TEER can be dominated by the transcellular pathway. This is true for tight epithelia already under resting conditions and, in leaky epithelia, after activation of ion channels.