TY - JOUR AU - Begley, D. J. AU - Brightman, M. W. PY - 2003 DA - 2003// TI - Structural and functional aspects of the blood–brain barrier JO - Prog Drug Res VL - 61 ID - Begley2003 ER - TY - JOUR AU - Pardridge, W. M. AU - Buciak, J. L. AU - Friden, P. M. PY - 1991 DA - 1991// TI - Selective transport of an anti-transferrin receptor antibody through the blood–brain barrier in vivo JO - J Pharmacol Exp Ther VL - 259 ID - Pardridge1991 ER - TY - JOUR AU - Yu, Y. J. AU - Zhang, Y. AU - Kenrick, M. AU - Hoyte, K. AU - Luk, W. AU - Lu, Y. AU - Atwal, J. AU - Elliott, J. M. AU - Prabhu, S. AU - Watts, R. J. AU - Dennis, M. S. PY - 2011 DA - 2011// TI - Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target JO - Sci Transl Med VL - 3 ID - Yu2011 ER - TY - JOUR AU - Coloma, M. J. AU - Lee, H. J. AU - Kurihara, A. AU - Landaw, E. M. AU - Boado, R. J. AU - Morrison, S. L. AU - Pardridge, W. M. PY - 2000 DA - 2000// TI - Transport across the primate blood–brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor JO - Pharm Res VL - 17 UR - https://doi.org/10.1023/A:1007592720793 DO - 10.1023/A:1007592720793 ID - Coloma2000 ER - TY - JOUR AU - Boado, R. J. AU - Hui, E. K. AU - Lu, J. Z. AU - Zhou, Q. H. AU - Pardridge, W. M. PY - 2010 DA - 2010// TI - Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein JO - J Biotechnol VL - 146 UR - https://doi.org/10.1016/j.jbiotec.2010.01.011 DO - 10.1016/j.jbiotec.2010.01.011 ID - Boado2010 ER - TY - JOUR AU - Demeule, M. AU - Currie, J. C. AU - Bertrand, Y. AU - Che, C. AU - Nguyen, T. AU - Regina, A. AU - Gabathuler, R. AU - Castaigne, J. P. AU - Beliveau, R. PY - 2008 DA - 2008// TI - Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2 JO - J Neurochem VL - 106 UR - https://doi.org/10.1111/j.1471-4159.2008.05492.x DO - 10.1111/j.1471-4159.2008.05492.x ID - Demeule2008 ER - TY - JOUR AU - Gabathuler, R. PY - 2010 DA - 2010// TI - Development of new peptide vectors for the transport of therapeutic across the blood–brain barrier JO - Ther Deliv VL - 1 UR - https://doi.org/10.4155/tde.10.35 DO - 10.4155/tde.10.35 ID - Gabathuler2010 ER - TY - JOUR AU - Ohshima-Hosoyama, S. AU - Hosoyama, T. AU - Nelon, L. D. AU - Keller, C. PY - 2010 DA - 2010// TI - IGF-1 receptor inhibition by picropodophyllin in medulloblastoma JO - Biochem Biophys Res Commun VL - 399 UR - https://doi.org/10.1016/j.bbrc.2010.08.009 DO - 10.1016/j.bbrc.2010.08.009 ID - Ohshima-Hosoyama2010 ER - TY - JOUR AU - Yang, C. AU - Robbins, P. D. PY - 2011 DA - 2011// TI - The roles of tumor-derived exosomes in cancer pathogenesis JO - Clin Dev Immunol VL - 2011 ID - Yang2011 ER - TY - JOUR AU - Thery, C. PY - 2011 DA - 2011// TI - Exosomes: secreted vesicles and intercellular communications JO - F1000 Biol Rep VL - 3 UR - https://doi.org/10.3410/B3-15 DO - 10.3410/B3-15 ID - Thery2011 ER - TY - JOUR AU - Cocucci, E. AU - Racchetti, G. AU - Meldolesi, J. PY - 2009 DA - 2009// TI - Shedding microvesicles: artefacts no more JO - Trends Cell Biol VL - 19 UR - https://doi.org/10.1016/j.tcb.2008.11.003 DO - 10.1016/j.tcb.2008.11.003 ID - Cocucci2009 ER - TY - JOUR AU - Pant, S. AU - Hilton, H. AU - Burczynski, M. E. PY - 2012 DA - 2012// TI - The multifaceted exosome: biogenesis, role in normal and aberrant cellular function, and frontiers for pharmacological and biomarker opportunities JO - Biochem Pharmacol VL - 83 UR - https://doi.org/10.1016/j.bcp.2011.12.037 DO - 10.1016/j.bcp.2011.12.037 ID - Pant2012 ER - TY - JOUR AU - Thery, C. AU - Amigorena, S. AU - Raposo, G. AU - Clayton, A. PY - 2006 DA - 2006// TI - Isolation and characterization of exosomes from cell culture supernatants and biological fluids JO - Curr Protoc Cell Biol VL - 3 ID - Thery2006 ER - TY - JOUR AU - Simpson, R. J. AU - Jensen, S. S. AU - Lim, J. W. PY - 2008 DA - 2008// TI - Proteomic profiling of exosomes: current perspectives JO - Proteomics VL - 8 UR - https://doi.org/10.1002/pmic.200800109 DO - 10.1002/pmic.200800109 ID - Simpson2008 ER - TY - JOUR AU - Mathivanan, S. AU - Fahner, C. J. AU - Reid, G. E. AU - Simpson, R. J. PY - 2012 DA - 2012// TI - ExoCarta 2012: database of exosomal proteins JO - RNA and lipids. Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gkr828 DO - 10.1093/nar/gkr828 ID - Mathivanan2012 ER - TY - JOUR AU - Smalheiser, N. R. PY - 2009 DA - 2009// TI - Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles? JO - Cardiovasc Psychiatry Neurol VL - 2009 UR - https://doi.org/10.1155/2009/383086 DO - 10.1155/2009/383086 ID - Smalheiser2009 ER - TY - JOUR AU - Vella, L. J. AU - Sharples, R. A. AU - Nisbet, R. M. AU - Cappai, R. AU - Hill, A. F. PY - 2008 DA - 2008// TI - The role of exosomes in the processing of proteins associated with neurodegenerative diseases JO - Eur Biophys J VL - 37 UR - https://doi.org/10.1007/s00249-007-0246-z DO - 10.1007/s00249-007-0246-z ID - Vella2008 ER - TY - JOUR AU - Segura, E. AU - Amigorena, S. AU - Thery, C. PY - 2005 DA - 2005// TI - Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses JO - Blood Cells Mol Dis VL - 35 UR - https://doi.org/10.1016/j.bcmd.2005.05.003 DO - 10.1016/j.bcmd.2005.05.003 ID - Segura2005 ER - TY - JOUR AU - Liu, M. L. AU - Williams, K. J. PY - 2012 DA - 2012// TI - Microvesicles: potential markers and mediators of endothelial dysfunction JO - Curr Opin Endocrinol Diabetes Obes VL - 19 UR - https://doi.org/10.1097/MED.0b013e32835057e9 DO - 10.1097/MED.0b013e32835057e9 ID - Liu2012 ER - TY - JOUR AU - Virgintino, D. AU - Rizzi, M. AU - Errede, M. AU - Strippoli, M. AU - Girolamo, F. AU - Bertossi, M. AU - Roncali, L. PY - 2012 DA - 2012// TI - Plasma membrane-derived microvesicles released from tip endothelial cells during vascular sprouting JO - Angiogenesis VL - 15 UR - https://doi.org/10.1007/s10456-012-9292-y DO - 10.1007/s10456-012-9292-y ID - Virgintino2012 ER - TY - JOUR AU - Clayton, A. AU - Mason, M. D. PY - 2009 DA - 2009// TI - Exosomes in tumour immunity JO - Curr Oncol VL - 16 UR - https://doi.org/10.3747/co.v16i3.367 DO - 10.3747/co.v16i3.367 ID - Clayton2009 ER - TY - JOUR AU - Chivet, M. AU - Hemming, F. AU - Pernet-Gallay, K. AU - Fraboulet, S. AU - Sadoul, R. PY - 2012 DA - 2012// TI - Emerging role of neuronal exosomes in the central nervous system JO - Front Physiol VL - 3 UR - https://doi.org/10.3389/fphys.2012.00145 DO - 10.3389/fphys.2012.00145 ID - Chivet2012 ER - TY - JOUR AU - Lachenal, G. AU - Pernet-Gallay, K. AU - Chivet, M. AU - Hemming, F. J. AU - Belly, A. AU - Bodon, G. AU - Blot, B. AU - Haase, G. AU - Goldberg, Y. AU - Sadoul, R. PY - 2011 DA - 2011// TI - Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity JO - Mol Cell Neurosci VL - 46 UR - https://doi.org/10.1016/j.mcn.2010.11.004 DO - 10.1016/j.mcn.2010.11.004 ID - Lachenal2011 ER - TY - JOUR AU - Weksler, B. B. AU - Subileau, E. A. AU - Perriere, N. AU - Charneau, P. AU - Holloway, K. AU - Leveque, M. AU - Tricoire-Leignel, H. AU - Nicotra, A. AU - Bourdoulous, S. AU - Turowski, P. AU - Male, D. K. AU - Roux, F. AU - Greenwood, J. AU - Romero, I. A. AU - Couraud, P. O. PY - 2005 DA - 2005// TI - Blood–brain barrier-specific properties of a human adult brain endothelial cell line JO - FASEB J VL - 19 ID - Weksler2005 ER - TY - JOUR AU - Wisniewski, J. R. AU - Zougman, A. AU - Nagaraj, N. AU - Mann, M. PY - 2009 DA - 2009// TI - Universal sample preparation method for proteome analysis JO - Nat Methods VL - 6 UR - https://doi.org/10.1038/nmeth.1322 DO - 10.1038/nmeth.1322 ID - Wisniewski2009 ER - TY - JOUR AU - Hirosawa, M. AU - Hoshida, M. AU - Ishikawa, M. AU - Toya, T. PY - 1993 DA - 1993// TI - MASCOT: multiple alignment system for protein sequences based on three-way dynamic programming JO - Comput Appl Biosci VL - 9 ID - Hirosawa1993 ER - TY - JOUR AU - Haqqani, A. S. AU - Kelly, J. F. AU - Stanimirovic, D. B. PY - 2008 DA - 2008// TI - Quantitative protein profiling by mass spectrometry using label-free proteomics JO - Methods Mol Biol VL - 439 UR - https://doi.org/10.1007/978-1-59745-188-8_17 DO - 10.1007/978-1-59745-188-8_17 ID - Haqqani2008 ER - TY - CHAP AU - Haqqani, A. S. AU - Caram-Salas, N. AU - Ding, W. AU - Brunette, E. AU - Delaney, C. E. AU - Baumann, E. AU - Boileau, E. AU - Stanimirovic, D. B. PY - 2012 DA - 2012// TI - Multiplexed evaluation of serum and CSF pharmacokinetics of brain-targeting single-domain antibodies using nanoLC-SRM-ILIS method BT - Mol Pharm ID - Haqqani2012 ER - TY - JOUR AU - Haqqani, A. S. AU - Stanimirovic, D. B. PY - 2011 DA - 2011// TI - Intercellular interactomics of human brain endothelial cells and th17 lymphocytes: a novel strategy for identifying therapeutic targets of CNS inflammation JO - Cardiovasc Psychiatry Neurol VL - 2011 UR - https://doi.org/10.1155/2011/175364 DO - 10.1155/2011/175364 ID - Haqqani2011 ER - TY - JOUR AU - Yu, L. R. AU - Conrads, T. P. AU - Uo, T. AU - Kinoshita, Y. AU - Morrison, R. S. AU - Lucas, D. A. AU - Chan, K. C. AU - Blonder, J. AU - Issaq, H. J. AU - Veenstra, T. D. PY - 2004 DA - 2004// TI - Global analysis of the cortical neuron proteome JO - Mol Cell Proteomics VL - 3 UR - https://doi.org/10.1074/mcp.M400034-MCP200 DO - 10.1074/mcp.M400034-MCP200 ID - Yu2004 ER - TY - JOUR AU - Abulrob, A. AU - Sprong, H. AU - Van Bergen en, H. P. AU - Stanimirovic, D. PY - 2005 DA - 2005// TI - The blood–brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells JO - J Neurochem VL - 95 UR - https://doi.org/10.1111/j.1471-4159.2005.03463.x DO - 10.1111/j.1471-4159.2005.03463.x ID - Abulrob2005 ER - TY - JOUR AU - Muruganandam, A. AU - Tanha, J. AU - Narang, S. AU - Stanimirovic, D. PY - 2002 DA - 2002// TI - Selection of phage-displayed llama single-domain antibodies that transmigrate across human blood–brain barrier endothelium JO - FASEB J VL - 16 ID - Muruganandam2002 ER - TY - JOUR AU - Tanha, J. AU - Muruganandam, A. AU - Stanimirovic, D. PY - 2003 DA - 2003// TI - Phage display technology for identifying specific antigens on brain endothelial cells JO - Methods Mol Med VL - 89 ID - Tanha2003 ER - TY - JOUR AU - Thery, C. AU - Zitvogel, L. AU - Amigorena, S. PY - 2002 DA - 2002// TI - Exosomes: composition, biogenesis and function JO - Nat Rev Immunol VL - 2 ID - Thery2002 ER - TY - JOUR AU - Alvarez-Erviti, L. AU - Seow, Y. AU - Yin, H. AU - Betts, C. AU - Lakhal, S. AU - Wood, M. J. PY - 2011 DA - 2011// TI - Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes JO - Nat Biotechnol VL - 29 UR - https://doi.org/10.1038/nbt.1807 DO - 10.1038/nbt.1807 ID - Alvarez-Erviti2011 ER - TY - JOUR AU - Zhuang, X. AU - Xiang, X. AU - Grizzle, W. AU - Sun, D. AU - Zhang, S. AU - Axtell, R. C. AU - Ju, S. AU - Mu, J. AU - Zhang, L. AU - Steinman, L. AU - Miller, D. AU - Zhang, H. G. PY - 2011 DA - 2011// TI - Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain JO - Mol Ther VL - 19 UR - https://doi.org/10.1038/mt.2011.164 DO - 10.1038/mt.2011.164 ID - Zhuang2011 ER - TY - JOUR AU - Jones, A. R. AU - Shusta, E. V. PY - 2007 DA - 2007// TI - Blood–brain barrier transport of therapeutics via receptor-mediation JO - Pharm Res VL - 24 UR - https://doi.org/10.1007/s11095-007-9379-0 DO - 10.1007/s11095-007-9379-0 ID - Jones2007 ER - TY - JOUR AU - Dehouck, B. AU - Fenart, L. AU - Dehouck, M. P. AU - Pierce, A. AU - Torpier, G. AU - Cecchelli, R. PY - 1997 DA - 1997// TI - A new function for the LDL receptor: transcytosis of LDL across the blood–brain barrier JO - J Cell Biol VL - 138 UR - https://doi.org/10.1083/jcb.138.4.877 DO - 10.1083/jcb.138.4.877 ID - Dehouck1997 ER - TY - JOUR AU - Demeule, M. AU - Poirier, J. AU - Jodoin, J. AU - Bertrand, Y. AU - Desrosiers, R. R. AU - Dagenais, C. AU - Nguyen, T. AU - Lanthier, J. AU - Gabathuler, R. AU - Kennard, M. AU - Jefferies, W. A. AU - Karkan, D. AU - Tsai, S. AU - Fenart, L. AU - Cecchelli, R. AU - Beliveau, R. PY - 2002 DA - 2002// TI - High transcytosis of melanotransferrin (P97) across the blood–brain barrier JO - J Neurochem VL - 83 UR - https://doi.org/10.1046/j.1471-4159.2002.01201.x DO - 10.1046/j.1471-4159.2002.01201.x ID - Demeule2002 ER -