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Figure 1 | Fluids and Barriers of the CNS

Figure 1

From: Ependymal cells of the mouse brain express urate transporter 1 (URAT1)

Figure 1

Distribution of URAT1 in mouse brain. Paraffin sections from nine-week-old WT (A–F, coronal section; M–O, sagittal section) and URAT1 KO (G–L, coronal section) mice were stained with a polyclonal antibody to URAT1 (anti-URAT1 antibody) and counterstained with hematoxylin. Red squares in the diagrams indicate the region of the images while the lower panels show magnified images around the ependymal cells (represented as dotted squares in the upper panels). Images (B–D), (H–J) or (M–N) were obtained from the same sections, respectively. Scale bars, 200 μm and 10 μm in top and bottom row of (L), respectively; 200 μm in (M–O). LV, lateral ventricle; V3V, ventral third ventricle; D3V, dorsal third ventricle, AQ, aqueduct; 4V, fourth ventricle.

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