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Table 2 Average amplitude of fold changes in neuroprotective gene expression levels in E15, E19 and P2 animals relative to adults in the choroid plexus

From: Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection

 

TJ proteins

Transporters

Enzymes

E15

5.9 ± 1.4

23.5 ± 9.2

5.1 ± 1.1

E19

2.5 ± 0.6

3.6 ± 0.9

2.1 ± 0.2

P2

1.9 ± 0.3

3.2 ± 0.7

1.9 ± 0.2

E15 vs. E19

*

*

**

E15 vs. P2

**

**

***

E19 vs. P2

ns

ns

ns

  1. Data are expressed as mean ± SEM of trend-independent FC calculated back from Log2FCad “absolute” values for all the genes (but three), analyzed in this study and illustrated in Figures 2, 3, 4, 5, 7. Slc22a12, Fmo3 and Ugt2a1 were excluded because FCad values at E15 could not be calculated (see figure legends). “Absolute” values of Log2FCad correspond to the value reported in the different figures, except that negative signs were removed. This table thus illustrates the FC amplitude independently of the variation trend, whether expression levels are higher or lower in earlier stages compared to the adult.
  2. *, **, ***Statistical differences between developmental stages, analyzed by Kruskal-Wallis followed by Dunns multiple comparison test, p < 0.05, 0.01, 0.001, respectively. ns: not statistically different.
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Fluids and Barriers of the CNS

ISSN: 2045-8118