Figure 4
From: Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection
Developmental profiles of drug metabolizing enzymes. (A) shows gene expression profiles for different cytochrome P450 enzymes and epoxide hydrolases in the lateral ventricle choroid plexus. Cyp2u1 and Ephx1 display similar Log2 FCad during development, thus the developmental profile overlap on the graph. No expression for Cyp2u1 was detected at E15. (B) shows gene expression profiles for flavin-dependent monoxygenase. Fmo3 was undetectable at E15. (C) shows gene expression profiles for UDP glucuronosyltransferases and sulfotransferases. Ugt2a1 was detected in adult, but not at E15. (D) shows gene expression profiles for soluble glutathione-S-transferases, and (E) for microsomal glutathione-S-transferases. (F) shows expression profiles for genes involved in GSH synthesis and metabolism. MI, multiple isoforms. Other abbreviations, data analysis, and data expression as in Figures 2 and 3.