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Table 1 Effects of pericytes on transport rates of HIV-1(I-HIV) and albumin (I-Alb) and on transendothelial electrical resistance (TEER) in Monolayers of mouse brain microvascular Endothelial Cells (BMEC)

From: Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood–brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk

 

I-HIV

I-Alb

TEER

BMEC: no pericytes

11.5 +/− 0.9 (15)

6.2 +/− 0.4 (15)

60 +/− 3 (15)

BMEC: + pericytes

9.0 +/− 0.4 (14)*

6.3 +/− 0.3 (14)

75 +/− 4 (15)*

  1. Means are reported with their means =/- SE (n). I-HIV and I-Alb transport rates are in cm/min(10-6) and TEER is in Ω x cm2. *Statistically different from corresponding “no pericyte” group, p<0.05.
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Fluids and Barriers of the CNS

ISSN: 2045-8118