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Figure 1 | Fluids and Barriers of the CNS

Figure 1

From: The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects

Figure 1

Schematic presentation of the major compartments of the mammalian brain and routes for drug exchange; extracellular fluid (ECF), brain cells, lateral ventricular CSF, cisterna magna CSF and lumbar CSF, passive transport (black arrows) and active transport (white arrows), as well as metabolism and CSF turnover. Drug targets may be present at different sites within the brain.

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Fluids and Barriers of the CNS

ISSN: 2045-8118