Figure 2
From: Minocycline inhibits glial proliferation in the H-Tx rat model of congenital hydrocephalus
Microglia density (cells/μm3) in minocycline treated and untreated animals. The number of immunoreactive microglia in untreated hydrocephalic animals was significantly higher than in the minocycline-treated hydrocephalic group (p < 0.001). Minocycline treatment had no effect on control brains. There was a statistically significant increase between both control groups compared to the untreated hydrocephalic animals (p < 0.001). Data are mean ± SD, n = 5, cell counts were multiplied by 10-5 to get the actual cell number per per μm3.