Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts

Table 3 Three arachnoid cyst (AC) samples with chromosomal gains detected with DNA copy number variation (CNV) analysis.

Sample	CNV present in sample	CNV in region registered in the Database of Genomic Variants^a	Genes known to be present in region
AC_2006-051	arr 7p22.1(6498207-6600621)x3 arr 8p11.21(42175206-42281148)x3 arr 14q23.3(64978487-65093419)x3	Inversion and deletion No reports Inversion	GRID2IP, C7orf26, ZDHHC4 IKBVB, PLAT FUT8
AC_2005-056	arr 12q13.13(51746148-51886072)x3 arr 12q24.31(121446657-121547275)x3 arr 14q23.3(64978487-65105576)x3 arr 15q15.3(42468491-42598658)x3 arr 16p13.3(3431656-3522375)x3	Small gains, inversions, and loss spanning region No reports Inversion No reports Loss	ITGB7, ZNF740, CSAD, SOAT2, IGFBP6, SPRYD3 ZCCHC8, CLIP1 FUT8 CTDSPL2, CASC4 CLUAP1, C16orf90, NAT15, ZNF597
AC_2006-004	arr 10p12.31(21822848-21949193)x3 arr 11q12.3(62557724-62669857)x3 arr 12q13.3(51724073-51844567)x3 arr 16p13.3(3522375-3631656)x3 arr 17q21.31(38560627-38814457)x3 arr 19p13.12(14246734-14391382)x3	Loss Loss Loss Loss Loss Loss	MLLT10, C10orf140, C10orf114 SLC22A24 SOAT2, IGFBP6, CSAD, SPRYD3, TENC1 BTBD12, NLRC3, CLUAP1 NBR1, LOC100130581, TMEM106A, DDX39, CD97,

^aInformation extracted from the Database of Genomic Variants (http://projects.tcag.ca/variation/?source=hg18) as of October, 2009 [20].

ISSN: 2045-8118