Skip to main content

Table 3 Number of shunt responders/non-responders depending on results of lumbar puncture or ICP monitoring

From: Cerebrospinal fluid pulse pressure amplitude during lumbar infusion in idiopathic normal pressure hydrocephalus can predict response to shunting

 

Lumbar puncture

ICP monitoring*

 

CSFP wave amplitude

during opening phase

CSF wave amplitude

during lumbar infusion

ICP wave amplitude

 

< 2 mmHg

≥ 2 mmHg

< 4 mmHg

≥ 4 mmHg

< 4 mmHg

≥ 4 mmHg

Responder (n = 35)

13

22

4

31

1

34

Non-Responder (n = 10)

8

2

6

4

7

3

Statistics

Sensitivity = 63; Specificity = 80

PPV = 92; NPV = 38

Sensitivity = 88; Specificity = 60

PPV = 89; NPV = 60

Sensitivity = 97; Specificity = 70

PPV = 92; NPV = 88

  1. * Mean ICP wave amplitude from the period 11 p.m. to 7 a.m. PPV = Positive predictive value; NPV = Negative predictive value.