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Table 5 Correlation analysis between DTI metrics and immunohistochemical ranking scores.

From: Diffusion tensor imaging correlates with cytopathology in a rat model of neonatal hydrocephalus

  

IC

Fornix

CC

  

P11

P22/P23

P11

P22/P23

P11

P22/P23

  

R

p

R

p

R

p

R

p

R

p

R

p

GFAP

             
 

FA

-0.47

NS

-0.88

<0.05*

-0.48

NS

-0.52

NS

-0.89

<0.05*

n/d

n/d

 

MD

0.63

NS

0.79

NS

-0.18

NS

0.52

NS

0.78

NS

n/d

n/d

Iba-1

             
 

FA

-0.26

NS

-0.88

<0.05*

-0.45

NS

-0.62

NS

-0.78

NS

n/d

n/d

 

MD

0.79

NS

0.76

NS

-0.24

NS

0.49

NS

0.89

<0.05*

n/d

n/d

LFB

             
 

FA

n/d

n/d

0.74

NS

n/d

n/d

-0.03

NS

n/d

n/d

n/d

n/d

 

MD

n/d

n/d

-0.74

NS

n/d

n/d

-0.40

NS

n/d

n/d

n/d

n/d

  1. GFAP: glial fibrillary acidic protein for astrocytes, Iba-1: ionized calcium-binding adaptor molecule for microglia, LFB: luxol fast blue for myelin. Note: * significant correlation between DTI and immunohistochemical grading (Spearman test); 3 HCP and 2 control rats were used at P11; 3 HCP and 3 control rats were used at P22/P23; n/d: not detectable.